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4X1J
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BU of 4x1j by Molmil
X-ray crystal structure of the dimeric BMP antagonist NBL1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroblastoma suppressor of tumorigenicity 1
著者Thompson, T.B, Nolan, K, Kattamuri, C.
登録日2014-11-24
公開日2015-01-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Neuroblastoma Suppressor of Tumorigenicity 1 (NBL1): INSIGHTS FOR THE FUNCTIONAL VARIABILITY ACROSS BONE MORPHOGENETIC PROTEIN (BMP) ANTAGONISTS.
J.Biol.Chem., 290, 2015
7MRZ
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BU of 7mrz by Molmil
Structure of GDF11 bound to fused ActRIIB-ECD and Alk4-ECD with Anti-ActRIIB Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B,Activin receptor type-1B, Fab Heavy Chain, ...
著者Goebel, E.J, Kattamuri, C, Gipson, G.R, Thompson, T.B.
登録日2021-05-10
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of activin ligand traps using natural sets of type I and type II TGF beta receptors.
Iscience, 25, 2022
4JPH
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BU of 4jph by Molmil
Crystal structure of Protein Related to DAN and Cerberus (PRDC)
分子名称: CITRIC ACID, GLUTATHIONE, GLYCEROL, ...
著者Deng, X, Nolan, K.T, Kattamuri, C, Thompson, T.B.
登録日2013-03-19
公開日2013-07-24
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure of protein related to dan and cerberus: insights into the mechanism of bone morphogenetic protein antagonism.
Structure, 21, 2013
8E3G
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BU of 8e3g by Molmil
BMP2/GDF5 heterodimer
分子名称: Bone morphogenetic protein 2, GLYCEROL, Growth/differentiation factor 5
著者Gipson, G.R, Nolan, K.T, Thompson, T.B.
登録日2022-08-17
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers.
Bmc Biol., 21, 2023
7OLY
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BU of 7oly by Molmil
Structure of activin A in complex with an ActRIIB-Alk4 fusion reveal insight into activin receptor interactions
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-1B, ...
著者Hakansson, M, Rose, N.C, Castonguay, R, Logan, D.T, Krishnan, L.
登録日2021-05-20
公開日2022-02-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.265 Å)
主引用文献Structures of activin ligand traps using natural sets of type I and type II TGF beta receptors.
Iscience, 25, 2022
3B4V
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BU of 3b4v by Molmil
X-Ray structure of Activin in complex with FSTL3
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Inhibin beta A chain, ...
著者Thompson, T.B.
登録日2007-10-24
公開日2008-09-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity.
J.Biol.Chem., 283, 2008
3SEK
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BU of 3sek by Molmil
Crystal Structure of the Myostatin:Follistatin-like 3 Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Follistatin-related protein 3, Growth/differentiation factor 8
著者Cash, J.N, Thompson, T.B.
登録日2011-06-10
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Structure of myostatinfollistatin-like 3: N-terminal domains of follistatin-type molecules exhibit alternate modes of binding.
J.Biol.Chem., 287, 2012
5HK5
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BU of 5hk5 by Molmil
Structure of the Grem2-GDF5 Inhibitory Complex
分子名称: Gremlin-2, Growth/differentiation factor 5
著者Nolan, K, Thompson, T.B, Read, R.J.
登録日2016-01-13
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of Gremlin-2 in Complex with GDF5 Gives Insight into DAN-Family-Mediated BMP Antagonism.
Cell Rep, 16, 2016

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件を2024-08-28に公開中

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