6BWZ
| SYSGYS from low-complexity domain of FUS, residues 37-42 | 分子名称: | SYSGYS peptide from low-complexity domain of FUS | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Tamir, G, Eisenberg, D.S. | 登録日 | 2017-12-15 | 公開日 | 2018-04-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks. Science, 359, 2018
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6BXX
| GYNGFG from low-complexity domain of hnRNPA1, residues 243-248 | 分子名称: | hnRNPA1 | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S. | 登録日 | 2017-12-19 | 公開日 | 2018-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks. Science, 359, 2018
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6BZP
| STGGYG from low-complexity domain of FUS, residues 77-82 | 分子名称: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, RNA-binding protein FUS | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S. | 登録日 | 2017-12-25 | 公開日 | 2018-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.1 Å) | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks. Science, 359, 2018
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6BXV
| SYSSYGQS from low-complexity domain of FUS, residues 54-61 | 分子名称: | FUS | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S. | 登録日 | 2017-12-19 | 公開日 | 2018-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks. Science, 359, 2018
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6BZM
| GFGNFGTS from low-complexity/FG repeat domain of Nup98, residues 116-123 | 分子名称: | Nuclear pore complex protein Nup98-Nup96 | 著者 | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Chong, L, Gonen, T, Eisenberg, D.S. | 登録日 | 2017-12-24 | 公開日 | 2018-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.9 Å) | 主引用文献 | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks. Science, 359, 2018
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8TH1
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8TH7
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8TH6
| Crystal Structure of the G3BP1 NTF2-like domain bound to USP10 peptide | 分子名称: | 1,2-ETHANEDIOL, Ras GTPase-activating protein-binding protein 1, Ubiquitin carboxyl-terminal hydrolase 10 | 著者 | Hughes, M.P, Taylor, J.P, Yang, Z. | 登録日 | 2023-07-14 | 公開日 | 2024-03-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity. Cell Rep, 43, 2024
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8TH5
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7N8R
| FGTGFG segment from the Nucleoporin p54, residues 63-68 | 分子名称: | FGTGFG segment from the Nucleoporin p54, residues 63-68, trifluoroacetic acid | 著者 | Hughes, M.P, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2021-06-15 | 公開日 | 2022-02-16 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Extended beta-Strands Contribute to Reversible Amyloid Formation. Acs Nano, 16, 2022
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6WPQ
| GNYNVF from hnRNPA2-low complexity domain segment, residues 286-291, D290V variant | 分子名称: | Heterogeneous nuclear ribonucleoprotein A2 | 著者 | Lu, J, Cao, Q, Hughes, M.P, Sawaya, M.R, Boyer, D.R, Cascio, D, Eisenberg, D.S. | 登録日 | 2020-04-27 | 公開日 | 2020-08-19 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid. Nat Commun, 11, 2020
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6WQK
| hnRNPA2 Low complexity domain (LCD) determined by cryoEM | 分子名称: | MCherry fluorescent protein,Heterogeneous nuclear ribonucleoproteins A2/B1 chimera | 著者 | Lu, J, Cao, Q, Hughes, M.P, Sawaya, M.R, Boyer, D.R, Cascio, D, Eisenberg, D.S. | 登録日 | 2020-04-29 | 公開日 | 2020-08-26 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid. Nat Commun, 11, 2020
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8V1L
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5WMJ
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5WOR
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7K3C
| SGMGGIT segment 58-64 from Keratin-8 | 分子名称: | ETHANOL, SGMGGIT segment 58-64 from the low complexity domain of Keratin-8, TRIETHYLENE GLYCOL | 著者 | Murray, K.A, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2020-09-11 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nat.Struct.Mol.Biol., 29, 2022
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7K3Y
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7K3X
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5WIA
| Crystal structure of the segment, GNNSYS, from the low complexity domain of TDP-43, residues 370-375 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Trinh, H, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2017-07-18 | 公開日 | 2018-04-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.002 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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5WKD
| Crystal structure of the segment, GNNQGSN, from the low complexity domain of TDP-43, residues 300-306 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Trinh, H, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | 登録日 | 2017-07-25 | 公開日 | 2018-04-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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5WKB
| MicroED structure of the segment, NFGEFS, from the A315E familial variant of the low complexity domain of TDP-43, residues 312-317 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | 登録日 | 2017-07-24 | 公開日 | 2018-05-23 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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5WHN
| Crystal structure of the segment, NFGAFS, from the low complexity domain of TDP-43, residues 312-317 | 分子名称: | Segment of TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2017-07-17 | 公開日 | 2018-04-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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5WHP
| Crystal structure of the segment, NFGTFS, from the A315T familial variant of the low complexity domain of TDP-43, residues 312-317 | 分子名称: | Segment of TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2017-07-17 | 公開日 | 2018-05-23 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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5WIQ
| Crystal structure of the segment, GFNGGFG, from the low complexity domain of TDP-43, residues 396-402 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2017-07-19 | 公開日 | 2018-04-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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6B79
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