6WQK

hnRNPA2 Low complexity domain (LCD) determined by cryoEM

Summary for 6WQK

• Entry DOI: 10.2210/pdb6wqk/pdb
• Related: 6WPQ
• EMDB information: 21871
• Descriptor: MCherry fluorescent protein,Heterogeneous nuclear ribonucleoproteins A2/B1 chimera (1 entity in total)
• Functional Keywords: ribinucleoprotein, rna binding protein, low complexity domain, protein fibril
• Biological source: Anaplasma marginale; More
• Total number of polymer chains: 5
• Total formula weight: 228333.13

Authors

Lu, J.,Cao, Q.,Hughes, M.P.,Sawaya, M.R.,Boyer, D.R.,Cascio, D.,Eisenberg, D.S. (deposition date: 2020-04-29, release date: 2020-08-26, Last modification date: 2024-03-06)

• Primary citation: Lu, J.,Cao, Q.,Hughes, M.P.,Sawaya, M.R.,Boyer, D.R.,Cascio, D.,Eisenberg, D.S.; CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid.; Nat Commun, 11:4090-4090, 2020; PubMed: 32796831; DOI: 10.1038/s41467-020-17905-y

Experimental method

ELECTRON MICROSCOPY (3.1 Å)