7B5N
 
 | | Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1. | | 分子名称: | 5-azanylpentan-2-one, Cullin-1, E3 ubiquitin-protein ligase ARIH1, ... | | 著者 | Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | | 登録日 | 2020-12-05 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-03-10 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
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7B5R
 | | Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27 | | 分子名称: | Cullin-1, Cyclin-A2, Cyclin-dependent kinase 2, ... | | 著者 | Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | | 登録日 | 2020-12-07 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
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7B5S
 | | Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1 | | 分子名称: | Cullin-1, E3 ubiquitin-protein ligase ARIH1, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | | 登録日 | 2020-12-07 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
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7B5L
 | | Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1 | | 分子名称: | 5-azanylpentan-2-one, Cullin-1, Cyclin-A2, ... | | 著者 | Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | | 登録日 | 2020-12-04 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-03-10 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
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7B5M
 | | Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2 | | 分子名称: | Cullin-1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ... | | 著者 | Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | | 登録日 | 2020-12-05 | | 公開日 | 2021-02-17 | | 最終更新日 | 2021-03-10 | | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | | 主引用文献 | Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
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8RHZ
 | | Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated conformation - symmetry expanded unneddylated dimer | | 分子名称: | Cullin-9, E3 ubiquitin-protein ligase RBX1, ZINC ION | | 著者 | Hopf, L.V.M, Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | | 登録日 | 2023-12-17 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex.
Nat.Struct.Mol.Biol., 31, 2024
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8Q7E
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8Q7H
 | | Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused cullin dimer | | 分子名称: | Cullin-9, E3 ubiquitin-protein ligase RBX1, NEDD8, ... | | 著者 | Hopf, L.V.M, Horn-Ghetko, D, Schulman, B.A. | | 登録日 | 2023-08-16 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex.
Nat.Struct.Mol.Biol., 31, 2024
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5O74
 | | Crystal structure of human Rab1b covalently bound to the GEF domain of DrrA/SidM from Legionella pneumophila in the presence of GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Multifunctional virulence effector protein DrrA, Ras-related protein Rab-1B | | 著者 | Cigler, M, Mueller, T, Horn-Ghetko, D, von Wrisberg, M.K, Fottner, M, Goody, R.S, Itzen, A, Mueller, M.P, Lang, K. | | 登録日 | 2017-06-08 | | 公開日 | 2017-10-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Proximity-Triggered Covalent Stabilization of Low-Affinity Protein Complexes In Vitro and In Vivo.
Angew. Chem. Int. Ed. Engl., 56, 2017
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8C07
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7OD1
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7ONI
 | | Structure of Neddylated CUL5 C-terminal region-RBX2-ARIH2* | | 分子名称: | Cullin-5, E3 ubiquitin-protein ligase ARIH2, NEDD8, ... | | 著者 | Kostrhon, S.P, prabu, J.R, Schulman, B.A. | | 登録日 | 2021-05-25 | | 公開日 | 2021-09-15 | | 最終更新日 | 2021-10-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation.
Nat.Chem.Biol., 17, 2021
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8C06
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