8UA8
 
 | | Structure of Semliki Forest virus VLP in complex with VLDLR LA2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Assembly protein E3, ... | | 著者 | Abraham, J, Yang, P, Li, W, Fan, X, Pan, J. | | 登録日 | 2023-09-20 | | 公開日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structure of SFV VLP-VLDLRAD2 complex at the 3-fold axes
To Be Published
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3KAS
 | | Machupo virus GP1 bound to human transferrin receptor 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein, ... | | 著者 | Abraham, J, Corbett, K.D, Harrison, S.C. | | 登録日 | 2009-10-19 | | 公開日 | 2010-03-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses.
Nat.Struct.Mol.Biol., 17, 2010
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4MXW
 | | Structure of heterotrimeric lymphotoxin LTa1b2 bound to lymphotoxin beta receptor LTbR and anti-LTa Fab | | 分子名称: | Lymphotoxin-alpha, Lymphotoxin-beta, Tumor necrosis factor receptor superfamily member 3, ... | | 著者 | Sudhamsu, J, Yin, J.P, Hymowitz, S.G. | | 登録日 | 2013-09-26 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Dimerization of LT beta R by LT alpha 1 beta 2 is necessary and sufficient for signal transduction.
Proc.Natl.Acad.Sci.USA, 110, 2013
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1XWE
 | | NMR Structure of C345C (NTR) domain of C5 of complement | | 分子名称: | Complement C5 | | 著者 | Bramham, J, Thai, C.-T, Soares, D.C, Uhrin, D, Ogata, R.T, Barlow, P.N. | | 登録日 | 2004-10-30 | | 公開日 | 2004-12-21 | | 最終更新日 | 2021-11-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Functional Insights from the Structure of the Multifunctional C345C Domain of C5 of Complement
J.Biol.Chem., 280, 2005
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2FLQ
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3EC1
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1H67
 | | NMR Structure of the CH Domain of Calponin | | 分子名称: | CALPONIN ALPHA | | 著者 | Bramham, J, Smith, B.O, Uhrin, D, Barlow, P.N, Winder, S.J. | | 登録日 | 2001-06-07 | | 公開日 | 2002-02-14 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the Calponin Ch Domain and Fitting to the 3D-Helical Reconstruction of F-Actin:Calponin.
Structure, 10, 2002
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6WRX
 | | Crystal structure of computationally designed protein 2DS25.1 in complex with the human Transferrin receptor ectodomain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Abraham, J, Coscia, A, Olal, D, Sahtoe, D.D, Baker, D, Clark, L. | | 登録日 | 2020-04-30 | | 公開日 | 2021-04-28 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Transferrin receptor targeting by de novo sheet extension.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6WRV
 | | Crystal structure of computationally designed protein 3DS18 in complex with the human Transferrin receptor ectodomain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Computationally designed protein 3DS18, ... | | 著者 | Abraham, J, Baker, D, Sahtoe, D.D, Coscia, A, Clark, L, Olal, D. | | 登録日 | 2020-04-30 | | 公開日 | 2021-04-28 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Transferrin receptor targeting by de novo sheet extension.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6WRW
 | | Crystal structure of computationally designed protein 2DS25.5 in complex with the human Transferrin receptor ectodomain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Computationally designed protein 2DS25.5, ... | | 著者 | Abraham, J, Coscia, A, Olal, D, Sahtoe, D.D, Baker, D, Clark, L. | | 登録日 | 2020-04-30 | | 公開日 | 2021-04-28 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Transferrin receptor targeting by de novo sheet extension.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7OZR
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8UA4
 | | Structure of eastern equine encephalitis virus VLP in complex with VLDLR LA1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ... | | 著者 | Abraham, J, Yang, P, Li, W, Fan, X, Pan, J. | | 登録日 | 2023-09-20 | | 公開日 | 2024-08-14 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Structural basis for VLDLR recognition by eastern equine encephalitis virus.
Nat Commun, 15, 2024
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8UA9
 | | Structure of eastern equine encephalitis virus VLP unliganded quasi-threefold spike protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, Envelope glycoprotein E1, ... | | 著者 | Abraham, J, Yang, P, Li, W, Fan, X, Pan, J. | | 登録日 | 2023-09-20 | | 公開日 | 2024-08-14 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis for VLDLR recognition by eastern equine encephalitis virus.
Nat Commun, 15, 2024
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7MFR
 | | Crystal Structure of a Fab fragment bound to peptide GGM | | 分子名称: | Antibody fragment - Heavy Chain of fab, Antibody fragment - Light Chain of fab, GLY-GLY-MET, ... | | 著者 | Sudhamsu, J. | | 登録日 | 2021-04-10 | | 公開日 | 2021-06-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.848 Å) | | 主引用文献 | Antibody toolkit reveals N-terminally ubiquitinated substrates of UBE2W.
Nat Commun, 12, 2021
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4MNE
 | | Crystal structure of the BRAF:MEK1 complex | | 分子名称: | 7-fluoro-3-[(2-fluoro-4-iodophenyl)amino]-N-{[(2S)-2-hydroxypropyl]oxy}furo[3,2-c]pyridine-2-carboxamide, CHLORIDE ION, Dual specificity mitogen-activated protein kinase kinase 1, ... | | 著者 | Sudhamsu, J, Haling, J.R, Morales, T, Brandhuber, B, Hymowitz, S.G. | | 登録日 | 2013-09-10 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.8483 Å) | | 主引用文献 | Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling.
Cancer Cell, 26, 2014
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4MNF
 | | Crystal structure of BRAF-V600E bound to GDC0879 | | 分子名称: | 2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethanol, CHLORIDE ION, Serine/threonine-protein kinase B-raf | | 著者 | Sudhamsu, J, Haling, J.R, Morales, T, Brandhuber, B, Hymowitz, S.G. | | 登録日 | 2013-09-10 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling.
Cancer Cell, 26, 2014
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2I7O
 | | Structure of Re(4,7-dimethyl-phen)(Thr124His)(Lys122Trp)(His83Gln)AzCu(II), a Rhenium modified Azurin mutant | | 分子名称: | (1,10 PHENANTHROLINE)-(TRI-CARBON MONOXIDE) RHENIUM (I), Azurin, COPPER (II) ION | | 著者 | Sudhamsu, J, Crane, B.R. | | 登録日 | 2006-08-31 | | 公開日 | 2007-08-14 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Tryptophan-accelerated electron flow through proteins.
Science, 320, 2008
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4O65
 | | Crystal structure of the cupredoxin domain of amoB from Nitrosocaldus yellowstonii | | 分子名称: | COPPER (II) ION, Putative archaeal ammonia monooxygenase subunit B, SULFATE ION | | 著者 | Lawton, T.J, Ham, J, Sun, T, Rosenzweig, A.C. | | 登録日 | 2013-12-20 | | 公開日 | 2014-04-02 | | 最終更新日 | 2014-11-12 | | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | | 主引用文献 | Structural conservation of the B subunit in the ammonia monooxygenase/particulate methane monooxygenase superfamily.
Proteins, 82, 2014
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6QNA
 | | Structure of bovine anti-RSV hybrid Fab B13HC-B4LC | | 分子名称: | B13 Heavy chain, B4 light chain, GLYCEROL | | 著者 | Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J. | | 登録日 | 2019-02-10 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019
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6QN9
 | | Structure of bovine anti-RSV Fab B4 | | 分子名称: | GLYCEROL, Heavy chain, SULFATE ION, ... | | 著者 | Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J. | | 登録日 | 2019-02-10 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019
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6QN7
 | | Structure of bovine anti-RSV hybrid Fab B4HC-B13LC | | 分子名称: | Heavy chain of bovine anti-RSV B4, Light chain of bovine anti-RSV B13 | | 著者 | Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J. | | 登録日 | 2019-02-10 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019
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6QN8
 | | Structure of bovine anti-RSV Fab B13 | | 分子名称: | CHLORIDE ION, Heavy chain of bovine anti-RSV B13 Fab, Light chain of bovine anti-RSV Fab B13 | | 著者 | Ren, J, Nettleship, J.E, Harris, G, Mwangi, W, Rhaman, N, Grant, C, Kotecha, A, Fry, E, Charleston, B, Stuart, D.I, Hammond, J, Owens, R.J. | | 登録日 | 2019-02-10 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.
Mol.Immunol., 112, 2019
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4UC0
 | | Crystal Structure Of a purine nucleoside phosphorylase (PSI-NYSGRC-029736) from Agrobacterium vitis | | 分子名称: | HYPOXANTHINE, Purine nucleoside phosphorylase | | 著者 | Cameron, S.A, Sampathkumar, P, Ramagopal, U.A, Attonito, J, Ahmed, M, Bhosle, R, Bonanno, J, Chamala, S, Chowdhury, S, Glenn, A.S, Hammonds, J, Hillerich, B, Love, J.D, Seidel, R, Stead, M, Toro, R, Wasserman, S.R, Schramm, V.L, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2014-08-13 | | 公開日 | 2014-10-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure Of a purine nucleoside phosphorylase (PSI-NYSGRC-029736) from Agrobacterium vitis
To be published
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4GF0
 | | Crystal structure of glutahtione transferase homolog from sulfitobacter, TARGET EFI-501084, with bound glutathione | | 分子名称: | CHLORIDE ION, GLUTATHIONE, Glutathione S-transferase | | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2012-08-02 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of glutahtione transferase homolog from sulfitobacter, TARGET EFI-501084, with bound glutathione
To be Published
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4Z44
 | | F454K Mutant of Tryptophan 7-halogenase PrnA | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent tryptophan halogenase PrnA, ... | | 著者 | Shepherd, S.A, Karthikeyan, C, Latham, J, Struck, A.-W, Thompson, M.L, Menon, B, Levy, C.W, Leys, D, Micklefield, J. | | 登録日 | 2015-04-01 | | 公開日 | 2016-04-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | | 主引用文献 | Extending the biocatalytic scope of regiocomplementary flavin-dependent halogenase enzymes.
Chem Sci, 6, 2015
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