6QN7
Structure of bovine anti-RSV hybrid Fab B4HC-B13LC
Summary for 6QN7
Entry DOI | 10.2210/pdb6qn7/pdb |
Descriptor | Heavy chain of bovine anti-RSV B4, Light chain of bovine anti-RSV B13 (3 entities in total) |
Functional Keywords | cattle antibodies, bovine respiratory syncytial virus, rsv, fab, hybrid fab, immune system |
Biological source | Bos taurus (cattle) More |
Total number of polymer chains | 4 |
Total formula weight | 95538.37 |
Authors | Ren, J.,Nettleship, J.E.,Harris, G.,Mwangi, W.,Rhaman, N.,Grant, C.,Kotecha, A.,Fry, E.,Charleston, B.,Stuart, D.I.,Hammond, J.,Owens, R.J. (deposition date: 2019-02-10, release date: 2019-05-29, Last modification date: 2019-08-21) |
Primary citation | Ren, J.,Nettleship, J.E.,Harris, G.,Mwangi, W.,Rhaman, N.,Grant, C.,Kotecha, A.,Fry, E.,Charleston, B.,Stuart, D.I.,Hammond, J.,Owens, R.J. The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus. Mol.Immunol., 112:123-130, 2019 Cited by PubMed: 31100550DOI: 10.1016/j.molimm.2019.04.026 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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