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4OWF
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BU of 4owf by Molmil
Crystal structure of the NEMO CoZi in complex with HOIP NZF1 domain
分子名称: E3 ubiquitin-protein ligase RNF31, NF-kappa-B essential modulator, ZINC ION
著者Rahighi, S, Fujita, H, Kawasaki, M, Kato, R, Iwai, K, Wakatsuki, S.
登録日2014-01-31
公開日2014-02-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism Underlying I kappa B Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex.
Mol.Cell.Biol., 34, 2014
5Y3T
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BU of 5y3t by Molmil
Crystal structure of hetero-trimeric core of LUBAC: HOIP double-UBA complexed with HOIL-1L UBL and SHARPIN UBL
分子名称: E3 ubiquitin-protein ligase RNF31, GLYCEROL, RanBP-type and C3HC4-type zinc finger-containing protein 1, ...
著者Tokunaga, A, Fujita, H, Ariyoshi, M, Ohki, I, Tochio, H, Iwai, K, Shirakawa, M.
登録日2017-07-31
公開日2018-05-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization.
Cell Rep, 23, 2018
3B08
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BU of 3b08 by Molmil
Crystal structure of the mouse HOIL1-L-NZF in complex with linear di-ubiquitin
分子名称: Polyubiquitin-C, RanBP-type and C3HC4-type zinc finger-containing protein 1, ZINC ION, ...
著者Sato, Y, Fujita, H, Yoshikawa, A, Yamashita, M, Yamagata, A, Kaiser, S.E, Iwai, K, Fukai, S.
登録日2011-06-07
公開日2011-12-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
Proc.Natl.Acad.Sci.USA, 108, 2011
3B0A
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BU of 3b0a by Molmil
Crystal structure of the mouse HOIL1-L-NZF in complex with linear di-ubiquitin
分子名称: Polyubiquitin-C, RanBP-type and C3HC4-type zinc finger-containing protein 1, TRIS(HYDROXYETHYL)AMINOMETHANE, ...
著者Sato, Y, Fujita, H, Yoshikawa, A, Yamashita, M, Yamagata, A, Kaiser, S.E, Iwai, K, Fukai, S.
登録日2011-06-07
公開日2011-12-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
Proc.Natl.Acad.Sci.USA, 108, 2011
5AZ2
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BU of 5az2 by Molmil
Crystal structure of the Fab fragment of 9E5, a murine monoclonal antibody specific for human epiregulin
分子名称: anti-human epiregulin antibody 9E5 Fab heavy chain, anti-human epiregulin antibody 9E5 Fab light chain
著者Kado, Y, Mizohata, E, Nagatoishi, S, Iijima, M, Shinoda, K, Miyafusa, T, Nakayama, T, Yoshizumi, T, Sugiyama, A, Kawamura, T, Lee, Y.H, Matsumura, H, Doi, H, Fujitani, H, Kodama, T, Shibasaki, Y, Tsumoto, K, Inoue, T.
登録日2015-09-16
公開日2015-12-09
最終更新日2020-02-26
実験手法X-RAY DIFFRACTION (1.603 Å)
主引用文献Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES
J.Biol.Chem., 291, 2016
5E8D
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BU of 5e8d by Molmil
Crystal structure of human epiregulin in complex with the Fab fragment of murine monoclonal antibody 9E5
分子名称: CHLORIDE ION, GLYCEROL, Proepiregulin, ...
著者Kado, Y, Mizohata, E, Nagatoishi, S, Iijima, M, Shinoda, K, Miyafusa, T, Nakayama, T, Yoshizumi, T, Sugiyama, A, Kawamura, T, Lee, Y.H, Matsumura, H, Doi, H, Fujitani, H, Kodama, T, Shibasaki, Y, Tsumoto, K, Inoue, T.
登録日2015-10-14
公開日2015-12-09
最終更新日2020-02-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES
J.Biol.Chem., 291, 2016
3WII
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BU of 3wii by Molmil
Crystal structure of the Fab fragment of B2212A, a murine monoclonal antibody specific for the third fibronectin domain (Fn3) of human ROBO1.
分子名称: anti-human ROBO1 antibody B2212A Fab heavy chain, anti-human ROBO1 antibody B2212A Fab light chain
著者Nakayama, T, Mizohata, E, Yamashita, T, Nagatoishi, S, Nakakido, M, Iwanari, H, Mochizuki, Y, Kado, Y, Yokota, Y, Sato, R, Tsumoto, K, Fujitani, H, Kodama, T, Hamakubo, T, Inoue, T.
登録日2013-09-12
公開日2015-01-21
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses
Protein Sci., 24, 2015
3WIH
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BU of 3wih by Molmil
Crystal structure of the third fibronectin domain (Fn3) of human ROBO1 in complex with the Fab fragment of murine monoclonal antibody B2212A.
分子名称: GLYCEROL, Roundabout homolog 1, anti-human ROBO1 antibody B2212A Fab heavy chain, ...
著者Nakayama, T, Mizohata, E, Yamashita, T, Nagatoishi, M, Iwanari, H, Mochizuki, Y, Kado, Y, Yokota, Y, Sato, R, Tsumoto, K, Fujitani, H, Kodama, T, Hamakubo, T, Inoue, T.
登録日2013-09-12
公開日2015-01-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses
Protein Sci., 24, 2015
4DBG
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BU of 4dbg by Molmil
Crystal structure of HOIL-1L-UBL complexed with a HOIP-UBA derivative
分子名称: RING finger protein 31, RanBP-type and C3HC4-type zinc finger-containing protein 1
著者Yagi, H, Hiromoto, T, Mizushima, T, Kurimoto, E, Kato, K.
登録日2012-01-15
公開日2012-04-04
最終更新日2012-05-16
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex
Embo Rep., 13, 2012
4ZFZ
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BU of 4zfz by Molmil
Crystal structure of rhesus macaque MHC class I molecule Mamu-B*098 complexed with myristoylated 5-mer lipopeptide derived from SIV Nef protein
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-mer lipopeptide from Protein Nef, ...
著者Morita, D, Sugita, M.
登録日2015-04-22
公開日2016-01-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.763 Å)
主引用文献Crystal structure of the N-myristoylated lipopeptide-bound MHC class I complex
Nat Commun, 7, 2016
5V8Q
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BU of 5v8q by Molmil
Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs): Part III
分子名称: 4-[(2S,3S)-2-ethyl-3-hydroxy-5-oxopyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile, Androgen receptor, GLYCEROL
著者Wilson, K.P.
登録日2017-03-22
公開日2017-05-24
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs) Part III: Discovery of 4-(5-oxopyrrolidine-1-yl)benzonitrile derivative 2f as a clinical candidate.
Bioorg. Med. Chem., 25, 2017
5T8J
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BU of 5t8j by Molmil
Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives
分子名称: 2-fluoro-4-[(2S,3S)-3-hydroxy-2,3-dimethylpyrrolidin-1-yl]-3-methylbenzonitrile, Androgen receptor, GLYCEROL
著者Wilson, K.P.
登録日2016-09-07
公開日2017-04-26
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives.
Bioorg. Med. Chem. Lett., 27, 2017
5T8E
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BU of 5t8e by Molmil
Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives
分子名称: 2-chloro-4-[(2S,3S)-3-hydroxy-2-methylpyrrolidin-1-yl]-3-methylbenzonitrile, Androgen receptor, GLYCEROL
著者Wilson, K.P.
登録日2016-09-07
公開日2017-04-26
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives.
Bioorg. Med. Chem. Lett., 27, 2017
6LF1
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BU of 6lf1 by Molmil
SeviL, a GM1b/asialo-GM1 binding lectin
分子名称: CHLORIDE ION, SeviL
著者Kamata, K, Ozeki, Y, Park, S.-Y, Tame, J.R.H.
登録日2019-11-28
公開日2020-12-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The structure of SeviL, a GM1b/asialo-GM1 binding R-type lectin from the mussel Mytilisepta virgata.
Sci Rep, 10, 2020
6LF2
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BU of 6lf2 by Molmil
SeviL bound to asialo-GM1 saccharide
分子名称: SeviL, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Kamata, K, Ozeki, Y, Park, S.-Y, Tame, J.R.H.
登録日2019-11-28
公開日2020-12-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structure of SeviL, a GM1b/asialo-GM1 binding R-type lectin from the mussel Mytilisepta virgata.
Sci Rep, 10, 2020
5XPU
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BU of 5xpu by Molmil
Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a monoclinic crystal
分子名称: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B
著者Hara, K, Taharazako, S, Hashimoto, H.
登録日2017-06-05
公開日2017-09-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP).
J. Biol. Chem., 292, 2017
5XPT
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BU of 5xpt by Molmil
Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a tetragonal crystal
分子名称: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B
著者Hara, K, Taharazako, S, Hashimoto, H.
登録日2017-06-05
公開日2017-09-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP).
J. Biol. Chem., 292, 2017
3W4S
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BU of 3w4s by Molmil
Myo-inositol kinase from Thermococcus kodakarensis
分子名称: Carbohydrate/pyrimidine kinase, PfkB family, IODIDE ION
著者Fujihashi, M, Miyamoto, Y, Miki, K.
登録日2013-01-10
公開日2017-02-22
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献An uncharacterized member of the ribokinase family in Thermococcus kodakarensis exhibits myo-inositol kinase activity.
J.Biol.Chem., 288, 2013
3W1D
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BU of 3w1d by Molmil
Structure of a pressure sensitive YFP variant YFP-G3
分子名称: Green Fluorescent protein
著者Imada, K, Yoshizawa, K, Kinoshita, M, Watanabe, T.M.
登録日2012-11-14
公開日2013-10-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Glycine insertion makes yellow fluorescent protein sensitive to hydrostatic pressure.
Plos One, 8, 2013
3W1C
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BU of 3w1c by Molmil
Structure of a pressure sensitive YFP variant YFP-G1
分子名称: Green Fluorescent protein
著者Imada, K, Yoshizawa, K, Kinoshita, M, Watanabe, T.M.
登録日2012-11-14
公開日2013-10-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Glycine insertion makes yellow fluorescent protein sensitive to hydrostatic pressure.
Plos One, 8, 2013
8J80
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BU of 8j80 by Molmil
Cryo-EM structure of hZnT7-Fab complex in zinc state 1, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-unbound conformation
分子名称: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ...
著者Han, B.B, Inaba, K, Watanabe, S.
登録日2023-04-28
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
8J7T
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BU of 8j7t by Molmil
Cryo-EM structure of hZnT7-Fab complex in zinc-unbound state, determined in outward-facing conformation
分子名称: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7
著者Han, B.B, Inaba, K, Watanabe, S.
登録日2023-04-28
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
8J7Y
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BU of 8j7y by Molmil
Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-bound state, determined in outward-facing conformation
分子名称: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ...
著者Han, B.B, Inaba, K, Watanabe, S.
登録日2023-04-28
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
8J7W
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BU of 8j7w by Molmil
Cryo-EM structure of hZnT7-Fab complex in zinc state 2, determined in heterogeneous conformations- one subunit in an inward-facing zinc-bound and the other in an outward-facing zinc-bound conformation
分子名称: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, ZINC ION, ...
著者Han, B.B, Inaba, K, Watanabe, S.
登録日2023-04-28
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023
8J7X
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BU of 8j7x by Molmil
Cryo-EM structure of hZnT7DeltaHis-loop-Fab complex in zinc-unbound state, determined in outward-facing conformation
分子名称: Heavy chain of YN7114-08 Fab, Light chain of YN7114-08 Fab, Zinc transporter 7
著者Han, B.B, Inaba, K, Watanabe, S.
登録日2023-04-28
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn 2+ uptake into the Golgi apparatus.
Nat Commun, 14, 2023

 

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