4DO8
 
 | | Crystal structure of the muscarinic toxin MT1 | | 分子名称: | ACETATE ION, Muscarinic toxin 1, THIOCYANATE ION | | 著者 | Fruchart-Gaillard, C, Mournier, G, Vera, L, Servent, D, Stura, E.A. | | 登録日 | 2012-02-09 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors.
Plos One, 7, 2012
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2VLW
 | | Crystal structure of the muscarinic toxin MT7 diiodoTYR51 derivative. | | 分子名称: | ACETATE ION, MUSCARINIC M1-TOXIN1, SULFATE ION | | 著者 | Menez, R, Granata, V, Mourier, G, Fruchart-Gaillard, C, Menez, A, Servant, D, Stura, E.A. | | 登録日 | 2008-01-17 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Different Interactions between Mt7 Toxin and the Human Muscarinic M1 Receptor in its Free and N-Methylscopolamine-Occupied States.
Mol.Pharmacol., 74, 2008
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3NEQ
 | | Crystal structure of the chimeric muscarinic toxin MT7 with loop 3 from MT1 | | 分子名称: | SULFATE ION, Three-finger muscarinic toxin 7 | | 著者 | Stura, E.A, Servent, D, Menez, R, Mournier, G, Menez, A, Fruchart-Gaillard, C. | | 登録日 | 2010-06-09 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors.
Plos One, 7, 2012
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3FEV
 | | Crystal structure of the chimeric muscarinic toxin MT7 with loop 1 from MT1. | | 分子名称: | Fusion of Muscarinic toxin 1, Muscarinic m1-toxin1, SULFATE ION | | 著者 | Stura, E.A, Menez, R, Mourier, G, Fruchart-Gaillard, C, Menez, A, Servant, D. | | 登録日 | 2008-12-01 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors.
Plos One, 7, 2012
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6TI9
 | | Human transthyretin (TTR) complexed with (E)-3-(((3,5-dibromo-2-hydroxybenzylidene)amino)oxy)propanoic acid. | | 分子名称: | 3-[(~{E})-[3,5-bis(bromanyl)-2-oxidanyl-phenyl]methylideneamino]oxypropanoic acid, GLYCEROL, S-1,2-PROPANEDIOL, ... | | 著者 | Ciccone, L, Nencetti, S, Orlandini, E, Rossello, A, Legrand, P, Shepard, W. | | 登録日 | 2019-11-22 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis.
Bioorg.Med.Chem., 28, 2020
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6TJN
 | | Human transthyretin (TTR) complexed with (E)-3-(((4-hydroxybenzylidene)amino)oxy)propanoic acid | | 分子名称: | 3-[(~{E})-(4-hydroxyphenyl)methylideneamino]oxypropanoic acid, Transthyretin | | 著者 | Ciccone, L, Shepard, W, Nencetti, S, Orlandini, E, Rossello, A. | | 登録日 | 2019-11-26 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis.
Bioorg.Med.Chem., 28, 2020
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7Z60
 | | Human transthyretin (TTR) complexed with Quercetin 3-O-beta-D-galactoside | | 分子名称: | 1,2-ETHANEDIOL, 2-[3,4-bis(oxidanyl)phenyl]-3-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5,7-bis(oxidanyl)chromen-4-one, IMIDAZOLE, ... | | 著者 | Ciccone, L, Braca, A, Orlandini, E, Nencetti, S. | | 登録日 | 2022-03-10 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Antioxidant Quercetin 3-O-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization
Crystals, 12, 2022
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2H5F
 | | Denmotoxin: A the three-finger toxin from colubrid snake Boiga dendrophila with bird-specific activity | | 分子名称: | PHOSPHATE ION, POTASSIUM ION, SODIUM ION, ... | | 著者 | Pawlak, J, Kini, R.M, Stura, E.A. | | 登録日 | 2006-05-26 | | 公開日 | 2006-08-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (Mangrove Catsnake) with bird-specific activity.
J.Biol.Chem., 281, 2006
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5N5Q
 | | Human TTR altered conformation from soaking in iron chloride. | | 分子名称: | ACETATE ION, FE (III) ION, Transthyretin, ... | | 著者 | Ciccone, L, Savko, M, Shepard, W, Stura, E.A. | | 登録日 | 2017-02-14 | | 公開日 | 2018-03-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Copper mediated amyloid-beta binding to Transthyretin.
Sci Rep, 8, 2018
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5N7C
 | | Human TTR altered conformation from soaking in CuCl2. | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, COPPER (II) ION, ... | | 著者 | Ciccone, L, Savko, M, Shepard, W, Stura, E.A. | | 登録日 | 2017-02-20 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Copper mediated amyloid-beta binding to Transthyretin.
Sci Rep, 8, 2018
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5N62
 | | Human TTR crystals soaked in manganese chloride. | | 分子名称: | MANGANESE (II) ION, Transthyretin | | 著者 | Ciccone, L, Savko, M, Shepard, W, Stura, E.A. | | 登録日 | 2017-02-14 | | 公開日 | 2018-03-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Copper mediated amyloid-beta binding to Transthyretin.
Sci Rep, 8, 2018
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2H7Z
 | | Crystal structure of irditoxin | | 分子名称: | Irditoxin subunit A, Irditoxin subunit B | | 著者 | Pawlak, J, Kini, R.M, Stura, E.A, Le Du, M.H. | | 登録日 | 2006-06-06 | | 公開日 | 2006-08-29 | | 最終更新日 | 2011-10-05 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity.
Faseb J., 23, 2009
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