3FEV
Crystal structure of the chimeric muscarinic toxin MT7 with loop 1 from MT1.
Summary for 3FEV
| Entry DOI | 10.2210/pdb3fev/pdb |
| Related | 2VLW |
| Descriptor | Fusion of Muscarinic toxin 1, Muscarinic m1-toxin1, SULFATE ION (3 entities in total) |
| Functional Keywords | chimera, acetylcholine receptor inhibitor, green mamba snake toxin, hm1 muscarinic receptor, toxin, neurotoxin, muscarinic toxin, postsynaptic neurotoxin, secreted |
| Biological source | Dendroaspis angusticeps (eastern green mamba) |
| Cellular location | Secreted : Q8QGR0 |
| Total number of polymer chains | 3 |
| Total formula weight | 22321.57 |
| Authors | Stura, E.A.,Menez, R.,Mourier, G.,Fruchart-Gaillard, C.,Menez, A.,Servant, D. (deposition date: 2008-12-01, release date: 2009-12-22, Last modification date: 2023-11-01) |
| Primary citation | Fruchart-Gaillard, C.,Mourier, G.,Blanchet, G.,Vera, L.,Gilles, N.,Menez, R.,Marcon, E.,Stura, E.A.,Servent, D. Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors. Plos One, 7:e39166-e39166, 2012 Cited by PubMed: 22720062DOI: 10.1371/journal.pone.0039166 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
Download full validation report
