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3ERA
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BU of 3era by Molmil
RECOMBINANT ERABUTOXIN A (S8T MUTANT)
Descriptor: ERABUTOXIN A, THIOCYANATE ION
Authors:Gaucher, J.F, Menez, R, Arnoux, B, Menez, A, Ducruix, A.
Deposit date:1997-06-25
Release date:1997-12-31
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High resolution x-ray analysis of two mutants of a curaremimetic snake toxin
Eur.J.Biochem., 267, 2000
1BGK
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BU of 1bgk by Molmil
SEA ANEMONE TOXIN (BGK) WITH HIGH AFFINITY FOR VOLTAGE DEPENDENT POTASSIUM CHANNEL, NMR, 15 STRUCTURES
Descriptor: BGK
Authors:Dauplais, M, Lecoq, A, Song, J, Cotton, J, Jamin, N, Gilquin, B, Roumestand, C, Vita, C, Harvey, A, Menez, A.
Deposit date:1996-05-08
Release date:1997-01-27
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures.
J.Biol.Chem., 272, 1997
1BF0
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BU of 1bf0 by Molmil
CALCICLUDINE (CAC) FROM GREEN MAMBA DENDROASPIS ANGUSTICEPS, NMR, 15 STRUCTURES
Descriptor: CALCICLUDINE
Authors:Gilquin, B, Lecoq, A, Desne, F, Guenneugues, M, Zinn-Justin, S, Menez, A.
Deposit date:1998-05-26
Release date:1999-01-13
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Conformational and functional variability supported by the BPTI fold: solution structure of the Ca2+ channel blocker calcicludine.
Proteins, 34, 1999
1QM7
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BU of 1qm7 by Molmil
X-ray structure of a three-fingered chimeric protein, stability of a structural scaffold
Descriptor: R-CHII
Authors:Le Du, M.H, Ricciardi, A, Khayati, M, Menez, R, Boulain, J.C, Menez, A, Ducancel, F.
Deposit date:1999-09-21
Release date:2000-03-15
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Stability of a Structural Scaffold Upon Activity Transfer : X-Ray Structure of a Three Fingers Chimeric Protein.
J.Mol.Biol., 296, 2000
1B45
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BU of 1b45 by Molmil
ALPHA-CNIA CONOTOXIN FROM CONUS CONSORS, NMR, 43 STRUCTURES
Descriptor: ALPHA-CNIA
Authors:Favreau, P, Krimm, I, Le Gall, F, Bobenrieth, M.J, Lamthanh, H, Bouet, F, Servent, D, Molgo, J, Menez, A, Letourneux, Y, Lancelin, J.M.
Deposit date:1999-01-05
Release date:1999-07-09
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Biochemical characterization and nuclear magnetic resonance structure of novel alpha-conotoxins isolated from the venom of Conus consors.
Biochemistry, 38, 1999
1BAH
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BU of 1bah by Molmil
A TWO DISULFIDE DERIVATIVE OF CHARYBDOTOXIN WITH DISULFIDE 13-33 REPLACED BY TWO ALPHA-AMINOBUTYRIC ACIDS, NMR, 30 STRUCTURES
Descriptor: CHARYBDOTOXIN
Authors:Song, J, Gilquin, B, Jamin, N, Guenneugues, M, Dauplais, M, Vita, C, Menez, A.
Deposit date:1996-06-06
Release date:1997-01-11
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:NMR solution structure of a two-disulfide derivative of charybdotoxin: structural evidence for conservation of scorpion toxin alpha/beta motif and its hydrophobic side chain packing.
Biochemistry, 36, 1997
2ERA
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BU of 2era by Molmil
RECOMBINANT ERABUTOXIN A, S8G MUTANT
Descriptor: ERABUTOXIN A
Authors:Gaucher, J.F, Menez, R, Arnoux, B, Menez, A, Ducruix, A.
Deposit date:1997-06-25
Release date:1997-12-31
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:High resolution x-ray analysis of two mutants of a curaremimetic snake toxin
Eur.J.Biochem., 267, 2000
2HEO
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BU of 2heo by Molmil
General Structure-Based Approach to the Design of Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers.
Descriptor: 5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Z-DNA binding protein 1
Authors:Magis, C, Gasparini, S, Charbonnier, J.B, Stura, E, Le Du, M.H, Menez, A, Cuniasse, P.
Deposit date:2006-06-21
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers.
J.Am.Chem.Soc., 128, 2006
2VLW
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BU of 2vlw by Molmil
Crystal structure of the muscarinic toxin MT7 diiodoTYR51 derivative.
Descriptor: ACETATE ION, MUSCARINIC M1-TOXIN1, SULFATE ION
Authors:Menez, R, Granata, V, Mourier, G, Fruchart-Gaillard, C, Menez, A, Servant, D, Stura, E.A.
Deposit date:2008-01-17
Release date:2008-10-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Different Interactions between Mt7 Toxin and the Human Muscarinic M1 Receptor in its Free and N-Methylscopolamine-Occupied States.
Mol.Pharmacol., 74, 2008
1FF4
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BU of 1ff4 by Molmil
X-RAY STRUCTURE OF MUSCARINIC TOXIN 2 AT 1.5 ANGSTROM RESOLUTION
Descriptor: MUSCARINIC TOXIN/ACETYLCHOLINE RECEPTOR BINDING PROTEIN, SULFATE ION
Authors:Menez, R, Le Du, M.H, Gaucher, J.F, Menez, A.
Deposit date:2000-07-25
Release date:2003-07-08
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:X-ray structure of muscarinic toxin 2 at 1.5 Angstrom resolution
To be Published
1CMR
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BU of 1cmr by Molmil
NMR SOLUTION STRUCTURE OF A CHIMERIC PROTEIN, DESIGNED BY TRANSFERRING A FUNCTIONAL SNAKE BETA-HAIRPIN INTO A SCORPION ALPHA/BETA SCAFFOLD (PH 3.5, 20C), NMR, 18 STRUCTURES
Descriptor: CHARYBDOTOXIN, ALPHA CHIMERA
Authors:Zinn-Justin, S, Guenneugues, M, Drakopoulou, E, Gilquin, B, Vita, C, Menez, A.
Deposit date:1996-03-15
Release date:1996-08-01
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Transfer of a beta-hairpin from the functional site of snake curaremimetic toxins to the alpha/beta scaffold of scorpion toxins: three-dimensional solution structure of the chimeric protein.
Biochemistry, 35, 1996
1QUZ
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BU of 1quz by Molmil
Solution structure of the potassium channel scorpion toxin HSTX1
Descriptor: HSTX1 TOXIN
Authors:Savarin, P, Romi-Lebrun, R, Zinn-Justin, S, Lebrun, B, Nakajima, T, Gilquin, B, Menez, A.
Deposit date:1999-07-05
Release date:2000-07-07
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structural and functional consequences of the presence of a fourth disulfide bridge in the scorpion short toxins: solution structure of the potassium channel inhibitor HsTX1.
Protein Sci., 8, 1999
1CXN
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BU of 1cxn by Molmil
REFINED THREE-DIMENSIONAL SOLUTION STRUCTURE OF A SNAKE CARDIOTOXIN: ANALYSIS OF THE SIDE-CHAIN ORGANISATION SUGGESTS THE EXISTENCE OF A POSSIBLE PHOSPHOLIPID BINDING SITE
Descriptor: CARDIOTOXIN GAMMA
Authors:Gilquin, B, Roumestand, C, Zinn-Justin, S, Menez, A, Toma, F.
Deposit date:1994-07-08
Release date:1994-12-20
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Refined three-dimensional solution structure of a snake cardiotoxin: analysis of the side-chain organization suggests the existence of a possible phospholipid binding site.
Biopolymers, 33, 1993
1NEA
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BU of 1nea by Molmil
THREE-DIMENSIONAL SOLUTION STRUCTURE OF A CURAREMIMETIC TOXIN FROM NAJA NIGRICOLLIS VENOM: A PROTON NMR AND MOLECULAR MODELING STUDY
Descriptor: TOXIN ALPHA
Authors:Zinn-Justin, S, Roumestand, C, Gilquin, B, Bontems, F, Menez, A, Toma, F.
Deposit date:1992-09-22
Release date:1993-10-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of a curaremimetic toxin from Naja nigricollis venom: a proton NMR and molecular modeling study.
Biochemistry, 31, 1992
1CXO
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BU of 1cxo by Molmil
REFINED THREE-DIMENSIONAL SOLUTION STRUCTURE OF A SNAKE CARDIOTOXIN: ANALYSIS OF THE SIDE-CHAIN ORGANISATION SUGGESTS THE EXISTENCE OF A POSSIBLE PHOSPHOLIPID BINDING SITE
Descriptor: CARDIOTOXIN GAMMA
Authors:Gilquin, B, Roumestand, C, Zinn-Justin, S, Menez, A, Toma, F.
Deposit date:1994-11-07
Release date:1994-12-20
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Refined three-dimensional solution structure of a snake cardiotoxin: analysis of the side-chain organization suggests the existence of a possible phospholipid binding site.
Biopolymers, 33, 1993
1G2G
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BU of 1g2g by Molmil
MINIMAL CONFORMATION OF THE ALPHA-CONOTOXIN IMI FOR THE ALPHA7 NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR RECOGNITION
Descriptor: ALPHA-CONOTOXIN IMI
Authors:Lamthanh, H, Jegou-Matheron, C, Servent, D, Menez, A, Lancelin, J.M.
Deposit date:2000-10-19
Release date:2000-11-08
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Minimal conformation of the alpha-conotoxin ImI for the alpha7 neuronal nicotinic acetylcholine receptor recognition: correlated CD, NMR and binding studies.
FEBS Lett., 454, 1999
1D5Q
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BU of 1d5q by Molmil
SOLUTION STRUCTURE OF A MINI-PROTEIN REPRODUCING THE CORE OF THE CD4 SURFACE INTERACTING WITH THE HIV-1 ENVELOPE GLYCOPROTEIN
Descriptor: CHIMERIC MINI-PROTEIN
Authors:Vita, C, Drakopoulou, E, Vizzanova, J, Rochette, S, Martin, L, Menez, A, Roumestand, C, Yang, Y.S, Ylisastigui, L, Benjouad, A, Gluckman, J.C.
Deposit date:1999-10-11
Release date:2000-10-11
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Rational engineering of a miniprotein that reproduces the core of the CD4 site interacting with HIV-1 envelope glycoprotein.
Proc.Natl.Acad.Sci.USA, 96, 1999
2GLQ
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BU of 2glq by Molmil
X-ray structure of human alkaline phosphatase in complex with strontium
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, placental type, ...
Authors:Llinas, P, Masella, M, Stigbrand, T, Menez, A, Stura, E.A, Le Du, M.H.
Deposit date:2006-04-05
Release date:2006-04-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural studies of human alkaline phosphatase in complex with strontium: Implication for its secondary effect in bones.
Protein Sci., 15, 2006
1IQ9
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BU of 1iq9 by Molmil
crystal structure at 1.8 A of toxin a from Naja nigricollis venom
Descriptor: SULFATE ION, alpha-neurotoxin
Authors:Menez, R, Le Du, M.H, Menez, A.
Deposit date:2001-07-10
Release date:2003-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Motions and structural variability within toxins: Implication for their use as scaffolds for protein engineering
Protein Sci., 12, 2003
1JN6
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BU of 1jn6 by Molmil
Crystal Structure of Fab-Estradiol Complexes
Descriptor: monoclonal anti-estradiol 10G6D6 Fab heavy chain, monoclonal anti-estradiol 10G6D6 Fab light chain
Authors:Monnet, C, Bettsworth, F, Stura, E.A, Le Du, M.-H, Menez, R, Derrien, L, Zinn-Justin, S, Gilquin, B, Sibai, G, Battail-Poirot, N, Jolivet, M, Menez, A, Arnaud, M, Ducancel, F, Charbonnier, J.B.
Deposit date:2001-07-23
Release date:2002-02-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.
J.Mol.Biol., 315, 2002
1JNL
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BU of 1jnl by Molmil
Crystal Structure of Fab-Estradiol Complexes
Descriptor: monoclonal anti-estradiol 17E12E5 immunoglobulin gamma-1 chain, monoclonal anti-estradiol 17E12E5 immunoglobulin kappa chain
Authors:Monnet, C, Bettsworth, F, Stura, E.A, Le Du, M.-H, Menez, R, Derrien, L, Zinn-Justin, S, Gilquin, B, Sibai, G, Battail-Poirot, N, Jolivet, M, Menez, A, Arnaud, M, Ducancel, F, Charbonnier, J.B.
Deposit date:2001-07-24
Release date:2002-02-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.
J.Mol.Biol., 315, 2002
1JNN
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Crystal Structure of Fab-Estradiol Complexes
Descriptor: ESTRADIOL, MONOCLONAL ANTI-ESTRADIOL 17E12E5 IMMUNOGLOBULIN GAMMA-1 CHAIN, MONOCLONAL ANTI-ESTRADIOL 17E12E5 IMMUNOGLOBULIN KAPPA CHAIN
Authors:Monnet, C, Bettsworth, F, Stura, E.A, Le Du, M.-H, Menez, R, Derrien, L, Zinn-Justin, S, Gilquin, B, Sibai, G, Battail-Poirot, N, Jolivet, M, Menez, A, Arnaud, M, Ducancel, F, Charbonnier, J.B.
Deposit date:2001-07-24
Release date:2002-02-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.
J.Mol.Biol., 315, 2002
1JNH
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Crystal Structure of Fab-Estradiol Complexes
Descriptor: ESTRADIOL-6 CARBOXYL-METHYL-OXIME, monoclonal anti-estradiol 10G6D6 Fab heavy chain, monoclonal anti-estradiol 10G6D6 Fab light chain
Authors:Monnet, C, Bettsworth, F, Stura, E.A, Le Du, M.-H, Menez, R, Derrien, L, Zinn-Justin, S, Gilquin, B, Sibai, G, Battail-Poirot, N, Jolivet, M, Menez, A, Arnaud, M, Ducancel, F, Charbonnier, J.B.
Deposit date:2001-07-24
Release date:2002-02-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.
J.Mol.Biol., 315, 2002
1SXM
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SCORPION TOXIN (NOXIUSTOXIN) WITH HIGH AFFINITY FOR VOLTAGE DEPENDENT POTASSIUM CHANNEL AND LOW AFFINITY FOR CALCIUM DEPENDENT POTASSIUM CHANNEL (NMR AT 20 DEGREES, PH3.5, 39 STRUCTURES)
Descriptor: NOXIUSTOXIN
Authors:Dauplais, M, Gilquin, B, Possani, L.D, Gurrola-Briones, G, Roumestand, C, Menez, A.
Deposit date:1995-09-07
Release date:1996-01-29
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Determination of the three-dimensional solution structure of noxiustoxin: analysis of structural differences with related short-chain scorpion toxins.
Biochemistry, 34, 1995
1EW2
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BU of 1ew2 by Molmil
CRYSTAL STRUCTURE OF A HUMAN PHOSPHATASE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, PHOSPHATASE, ...
Authors:Le Du, M.H, Stigbrand, T, Taussig, M.J, Menez, A, Stura, E.A.
Deposit date:2000-04-21
Release date:2001-04-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity.
J.Biol.Chem., 276, 2001

 

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