7Z60

Human transthyretin (TTR) complexed with Quercetin 3-O-beta-D-galactoside

Summary for 7Z60

• Entry DOI: 10.2210/pdb7z60/pdb
• Descriptor: Transthyretin, 1,2-ETHANEDIOL, 2-[3,4-bis(oxidanyl)phenyl]-3-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5,7-bis(oxidanyl)chromen-4-one, ... (5 entities in total)
• Functional Keywords: transthyretin, thyroid hormone-binding protein, ttr-que-3gal, protein transport
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 28150.25

Authors

Ciccone, L.,Braca, A.,Orlandini, E.,Nencetti, S. (deposition date: 2022-03-10, release date: 2022-05-18, Last modification date: 2025-10-01)

• Primary citation: Ciccone, L.,Tonali, N.,Fruchart-Gaillard, C.,Barlettani, L.,Rossello, A.,Braca, A.,Orlandini, E.,Nencetti, S.; Antioxidant Quercetin 3-O-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization; Crystals, 12:-, 2022; DOI: 10.3390/cryst12050638

Experimental method

X-RAY DIFFRACTION (1.4 Å)