3NEQ

Crystal structure of the chimeric muscarinic toxin MT7 with loop 3 from MT1

Summary for 3NEQ

• Entry DOI: 10.2210/pdb3neq/pdb
• Related: 1FF4 2VLW 3FEV
• Descriptor: Three-finger muscarinic toxin 7, SULFATE ION (3 entities in total)
• Functional Keywords: chimeric muscarinic toxin, hm1-muscarinic receptor, snake toxin, green mamba, toxin
• Biological source: Dendroaspis angusticeps (Eastern green mamba); More
• Cellular location: Secreted : Q8QGR0
• Total number of polymer chains: 2
• Total formula weight: 15577.72

Authors

Stura, E.A.,Servent, D.,Menez, R.,Mournier, G.,Menez, A.,Fruchart-Gaillard, C. (deposition date: 2010-06-09, release date: 2011-08-24, Last modification date: 2023-09-06)

• Primary citation: Fruchart-Gaillard, C.,Mourier, G.,Blanchet, G.,Vera, L.,Gilles, N.,Menez, R.,Marcon, E.,Stura, E.A.,Servent, D.; Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors.; Plos One, 7:e39166-e39166, 2012; PubMed: 22720062; DOI: 10.1371/journal.pone.0039166

Experimental method

X-RAY DIFFRACTION (1.25 Å)