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8G3G
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CryoEM structure of yeast recombination mediator Rad52
分子名称: DNA repair and recombination protein RAD52
著者Deveryshetty, J, Basore, K, Rau, M, Fitzpatrick, J.A.J, Antony, E.
登録日2023-02-07
公開日2023-11-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes.
Nat Commun, 14, 2023
8VUW
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ELIC5 with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc in open conformation
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-AMINO-ETHANETHIOL, Erwinia chrysanthemi ligand-gated ion channel
著者Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L.
登録日2024-01-29
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.
Nat Commun, 13, 2022
8D64
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ELIC with cysteamine in POPC nanodisc
分子名称: 2-AMINO-ETHANETHIOL, Erwinia ligand-gated ion channel
著者Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L.
登録日2022-06-06
公開日2022-11-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.
Nat Commun, 13, 2022
8D67
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ELIC3 with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc
分子名称: 2-AMINO-ETHANETHIOL, Erwinia ligand-gated ion channel
著者Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L.
登録日2022-06-06
公開日2022-11-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.
Nat Commun, 13, 2022
8D66
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ELIC with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-AMINO-ETHANETHIOL, Erwinia ligand-gated ion channel
著者Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L.
登録日2022-06-06
公開日2022-11-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.
Nat Commun, 13, 2022
8D65
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ELIC apo in 2:1:1 POPC:POPE:POPG nanodisc
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Erwinia ligand-gated ion channel
著者Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L.
登録日2022-06-06
公開日2022-11-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.
Nat Commun, 13, 2022
8D63
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ELIC apo in POPC nanodisc
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Erwinia ligand-gated ion channel
著者Petroff II, J.T, Deng, Z, Rau, M.J, Fitzpatrick, J.A.J, Yuan, P, Cheng, W.W.L.
登録日2022-06-06
公開日2022-11-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.
Nat Commun, 13, 2022
6VPS
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Cryo-EM structure of the amyloid core of Drosophila Orb2 isolated from head
分子名称: Translational regulator orb2
著者Hervas, R, Rau, M.J, Park, Y, Zhang, W, Murzin, A.G, Fitzpatrick, J.A.J, Scheres, S.H.W, Si, K.
登録日2020-02-04
公開日2020-03-18
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila
Science, 367, 2020
4DJB
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A Structural Basis for the Assembly and Functions of a Viral Polymer that Inactivates Multiple Tumor Suppressors
分子名称: E4-ORF3
著者Ou, H.D, Kwiatkowski, W, Deerinck, T.J, Noske, A, Blain, K.Y, Land, H.S, Soria, C, Powers, C.J, May, A.P, Shu, X, Tsien, R.Y, Fitzpatrick, J.A.J, Long, J.A, Ellisman, M.H, Choe, S, O'Shea, C.C.
登録日2012-02-01
公開日2012-10-31
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.053 Å)
主引用文献A Structural Basis for the Assembly and Functions of a Viral Polymer that Inactivates Multiple Tumor Suppressors.
Cell(Cambridge,Mass.), 151, 2012
8TWZ
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ELIC with Propylamine in spNW15 nanodiscs with 2:1:1 POPC:POPE:POPG
分子名称: 3-AMINOPROPANE, Erwinia chrysanthemi ligand-gated ion channel
著者Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L.
登録日2023-08-21
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
8TWV
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ELIC5 with Propylamine in spNW15 nanodiscs with 2:1:1 POPC:POPE:POPG
分子名称: 3-AMINOPROPANE, Gamma-aminobutyric-acid receptor subunit beta-1
著者Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L.
登録日2023-08-21
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
7TPQ
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Cryo-em structure of human prothrombinase on a nanodisc at 5.3 Angstrom resolution
分子名称: Activated factor Xa heavy chain, Coagulation factor Va, Factor X light chain
著者Di Cera, E, Ruben, E.A.
登録日2022-01-25
公開日2022-05-04
最終更新日2022-06-29
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Cryo-EM structure of the prothrombin-prothrombinase complex.
Blood, 139, 2022
7UX1
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EcMscK in an Open Conformation
分子名称: Mechanosensitive channel MscK
著者Mount, J.W, Yuan, P.
登録日2022-05-04
公開日2022-11-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structural basis for mechanotransduction in a potassium-dependent mechanosensitive ion channel.
Nat Commun, 13, 2022
7UW5
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EcMscK G924S mutant in a closed conformation
分子名称: Mechanosensitive channel MscK
著者Mount, J.W, Yuan, P.
登録日2022-05-02
公開日2022-11-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Structural basis for mechanotransduction in a potassium-dependent mechanosensitive ion channel.
Nat Commun, 13, 2022
7S9Z
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Helicobacter Hepaticus CcsBA Closed Conformation
分子名称: Cytochrome c biogenesis protein, HEME B/C, PHOSPHATIDYLETHANOLAMINE
著者Mendez, D.L, Lowder, E.P, Tillman, D.E, Sutherland, M.C, Collier, A.L, Rau, M.J, Fitzpatrick, J.A, Kranz, R.G.
登録日2021-09-21
公開日2021-12-22
最終更新日2022-01-12
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport.
Nat.Chem.Biol., 18, 2022
7S9Y
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Helicobacter Hepaticus CcsBA Open Conformation
分子名称: Cytochrome c biogenesis protein, HEME B/C, PHOSPHATIDYLETHANOLAMINE
著者Mendez, D.L, Lowder, E.P, Tillman, D.E, Sutherland, M.C, Collier, A.L, Rau, M.J, Fitzpatrick, J.A, Kranz, R.G.
登録日2021-09-21
公開日2021-12-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport.
Nat.Chem.Biol., 18, 2022
8F7C
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Cryo-EM structure of human pannexin 2
分子名称: Pannexin-2, Soluble cytochrome b562 fusion
著者He, Z, Yuan, P.
登録日2022-11-18
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Structural and functional analysis of human pannexin 2 channel.
Nat Commun, 14, 2023
8F35
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Apo ELIC in spMSP1D1 nanodiscs with 2:1:1 POPC:POPE:POPG
分子名称: Erwinia chrysanthemi ligand-gated ion channel
著者Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L.
登録日2022-11-09
公開日2023-11-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
8F33
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ELIC with Propylamine in saposin nanodiscs with 2:1:1 POPC:POPE:POPG
分子名称: 3-AMINOPROPANE, Erwinia chrysanthemi ligand-gated ion channel
著者Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L.
登録日2022-11-09
公開日2023-11-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
8F34
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ELIC with Propylamine in spMSP1D1 nanodiscs with 2:1:1 POPC:POPE:POPG
分子名称: 3-AMINOPROPANE, Erwinia chrysanthemi ligand-gated ion channel
著者Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L.
登録日2022-11-09
公開日2023-11-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
8F32
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ELIC with Propylamine in SMA nanodiscs with 2:1:1 POPC:POPE:POPG
分子名称: 3-AMINOPROPANE, Erwinia chrysanthemi ligand-gated ion channel
著者Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L.
登録日2022-11-09
公開日2023-11-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Nat Commun, 15, 2024
8FPT
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STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS DERIVED FROM HUMAN LEWY BODY DEMENTIA TISSUE
分子名称: Alpha-synuclein
著者Barclay, A.M, Dhavale, D.D, Borcik, C.G, Rau, M.J, Basore, K, Milchberg, M.H, Warmuth, O.A, Kotzbauer, P.T, Rienstra, C.M, Schwieters, C.D.
登録日2023-01-05
公開日2023-02-22
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue.
Biorxiv, 2023
7TPP
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Cryo-em structure of human prothrombin:prothrombinase at 4.1 Angstrom resolution
分子名称: Activated factor Xa heavy chain, Coagulation factor Va, Factor X light chain, ...
著者Di Cera, E, Ruben, E.A.
登録日2022-01-25
公開日2022-05-04
最終更新日2022-06-29
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM structure of the prothrombin-prothrombinase complex.
Blood, 139, 2022
6UW6
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Cryo-EM structure of the human TRPV3 K169A mutant determined in lipid nanodisc
分子名称: Transient receptor potential cation channel subfamily V member 3, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
著者Deng, Z, Yuan, P.
登録日2019-11-04
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Gating of human TRPV3 in a lipid bilayer.
Nat.Struct.Mol.Biol., 27, 2020
6UW9
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Cryo-EM structure of the human TRPV3 K169A mutant in the presence of 2-APB, determined in lipid nanodisc
分子名称: Transient receptor potential cation channel subfamily V member 3
著者Deng, Z, Yuan, P.
登録日2019-11-04
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.33 Å)
主引用文献Gating of human TRPV3 in a lipid bilayer.
Nat.Struct.Mol.Biol., 27, 2020

 

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