4DJB

A Structural Basis for the Assembly and Functions of a Viral Polymer that Inactivates Multiple Tumor Suppressors

Summary for 4DJB

Entry DOI	10.2210/pdb4djb/pdb
Descriptor	E4-ORF3 (2 entities in total)
Functional Keywords	adenovirus protein, rrm-like fold, hpv e2 dbd-like protein, tumor suppressor inactivation, nucleus, viral protein
Biological source	Human adenovirus 5 (HAdV-5)
Total number of polymer chains	2
Total formula weight	30301.06
Authors	Ou, H.D.,Kwiatkowski, W.,Deerinck, T.J.,Noske, A.,Blain, K.Y.,Land, H.S.,Soria, C.,Powers, C.J.,May, A.P.,Shu, X.,Tsien, R.Y.,Fitzpatrick, J.A.J.,Long, J.A.,Ellisman, M.H.,Choe, S.,O'Shea, C.C. (deposition date: 2012-02-01, release date: 2012-10-31, Last modification date: 2018-01-24)
Primary citation	Ou, H.D.,Kwiatkowski, W.,Deerinck, T.J.,Noske, A.,Blain, K.Y.,Land, H.S.,Soria, C.,Powers, C.J.,May, A.P.,Shu, X.,Tsien, R.Y.,Fitzpatrick, J.A.,Long, J.A.,Ellisman, M.H.,Choe, S.,O'Shea, C.C. A Structural Basis for the Assembly and Functions of a Viral Polymer that Inactivates Multiple Tumor Suppressors. Cell(Cambridge,Mass.), 151:304-319, 2012 Cited by PubMed: 23063122 DOI: 10.1016/j.cell.2012.08.035 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.053 Å)

Structure validation