4DJB

A Structural Basis for the Assembly and Functions of a Viral Polymer that Inactivates Multiple Tumor Suppressors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	E4-ORF3	polymer	130	15150.5	2	UniProt (P04489) Pfam (PF06931) In PDB	Human adenovirus 5 (HAdV-5)	early E4 11 kDa protein
2		water	water		18.0	116	Chemie (HOH)

Sequence modifications

A, B: 1 - 116 (UniProt: P04489)

PDB	External Database	Details
Mse -13	-	EXPRESSION TAG
Gly -12	-	EXPRESSION TAG
Ser -11	-	EXPRESSION TAG
Ser -10	-	EXPRESSION TAG
His -9	-	EXPRESSION TAG
His -8	-	EXPRESSION TAG
His -7	-	EXPRESSION TAG
His -6	-	EXPRESSION TAG
His -5	-	EXPRESSION TAG
His -4	-	EXPRESSION TAG
Ser -3	-	EXPRESSION TAG
Gln -2	-	EXPRESSION TAG
Asp -1	-	EXPRESSION TAG
Pro 0	-	EXPRESSION TAG
Ser 71	Cys 71	ENGINEERED MUTATION
Glu 82	Asn 82	ENGINEERED MUTATION
Ser 86	Cys 86	ENGINEERED MUTATION

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30301.1
All*	Total formula weight	30301.1

*Water molecules are not included.