4DJB

A Structural Basis for the Assembly and Functions of a Viral Polymer that Inactivates Multiple Tumor Suppressors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	E4-ORF3	polymer	130	15150.5	2	UniProt (P04489) Pfam (PF06931)	Human adenovirus 5 (HAdV-5)	early E4 11 kDa protein
2	C, D (A, B)	water	water		18.0	116	Chemie (HOH)

Sequence modifications

A, B: 1 - 116 (UniProt: P04489)

PDB	External Database	Details
Mse -13	-	expression tag
Gly -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Ser -3	-	expression tag
Gln -2	-	expression tag
Asp -1	-	expression tag
Pro 0	-	expression tag
Ser 71	Cys 71	engineered mutation
Glu 82	Asn 82	engineered mutation
Ser 86	Cys 86	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30301.1
All*	Total formula weight	30301.1

*Water molecules are not included.