7ZCY
 
 | | Sporosarcina pasteurii urease (SPU) co-crystallized in the presence of an Ebselen-derivative and bound to Se atoms | | 分子名称: | 1,2-ETHANEDIOL, HYDROXIDE ION, N-(2-chloranyl-4-fluoranyl-phenyl)-2-selanyl-benzamide, ... | | 著者 | Mazzei, L, Ciurli, S, Cianci, M. | | 登録日 | 2022-03-29 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Optimized Ebselen-Based Inhibitors of Bacterial Ureases with Nontypical Mode of Action.
J.Med.Chem., 66, 2023
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7TIL
 | | CryoEM structure of JetD from Pseudomonas aeruginosa | | 分子名称: | JetD | | 著者 | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | | 登録日 | 2022-01-13 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA.
Mol.Cell, 82, 2022
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8DK2
 | | CryoEM structure of Pseudomonas aeruginosa PA14 JetABC in an unclamped state trapped in ATP dependent dimeric form | | 分子名称: | DNA (26-MER), JetA, JetB, ... | | 著者 | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | | 登録日 | 2022-07-01 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA.
Mol.Cell, 82, 2022
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8DK3
 | | CryoEM structure of Pseudomonas aeruginosa PA14 JetC ATPase domain bound to DNA and cWHD domain of JetA | | 分子名称: | DNA (26-MER), JetA, JetC, ... | | 著者 | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | | 登録日 | 2022-07-01 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA.
Mol.Cell, 82, 2022
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8DK1
 | | CryoEM structure of JetABC (head construct) from Pseudomonas aeruginosa PA14 | | 分子名称: | JetA, JetB, JetC | | 著者 | Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K. | | 登録日 | 2022-07-01 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA.
Mol.Cell, 82, 2022
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6UXF
 | | Structure of V. metoecus NucC, hexamer form | | 分子名称: | Vibrio meotecus sp. RC341 NucC | | 著者 | Ye, Q, Corbett, K.D. | | 登録日 | 2019-11-07 | | 公開日 | 2019-12-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.
Mol.Cell, 77, 2020
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6UXG
 | | Structure of V. metoecus NucC, trimer form | | 分子名称: | SULFATE ION, Vibrio metoecus sp. RC341 NucC | | 著者 | Ye, Q, Corbett, K.D. | | 登録日 | 2019-11-07 | | 公開日 | 2019-12-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.
Mol.Cell, 77, 2020
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6P7P
 | | Structure of E. coli MS115-1 NucC, cAAA-bound form | | 分子名称: | CHLORIDE ION, Cyclic tri-AMP (5'-3' linked), E. coli MS115-1 NucC 2-241 | | 著者 | Ye, Q, Lau, R.K, Berg, K.R, Corbett, K.D. | | 登録日 | 2019-06-06 | | 公開日 | 2019-12-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.665 Å) | | 主引用文献 | Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.
Mol.Cell, 77, 2020
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6P7O
 | | Structure of E. coli MS115-1 NucC, Apo form | | 分子名称: | CHLORIDE ION, E. coli MS115-1 NucC, HEXAETHYLENE GLYCOL, ... | | 著者 | Ye, Q, Lau, R.K, Berg, K.R, Corbett, K.D. | | 登録日 | 2019-06-06 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.752 Å) | | 主引用文献 | Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.
Mol.Cell, 77, 2020
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6P7Q
 | | Structure of E. coli MS115-1 NucC, 5'-pApA bound form | | 分子名称: | CHLORIDE ION, E. coli MS115-1 NucC, RNA (5'-R(P*AP*A)-3') | | 著者 | Ye, Q, Lau, R.K, Berg, K.R, Corbett, K.D. | | 登録日 | 2019-06-06 | | 公開日 | 2019-12-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.
Mol.Cell, 77, 2020
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6Q1H
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6P8O
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8Q7S
 | | Crystal structure of the SARS-CoV-2 RBD (Wuhan) with neutralizing VHHs Ma6F06 and Re21H01 | | 分子名称: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, GLYCEROL, ... | | 著者 | Guttler, T, Aksu, M, Gorlich, D. | | 登録日 | 2023-08-16 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res., 221, 2023
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8Q93
 | | Crystal structure of the SARS-COV-2 RBD with neutralizing-VHHs Re30H02 and Re21D01 | | 分子名称: | Nanobody Re21D01, Nanobody Re30H02, Spike protein S1 | | 著者 | Aksu, M, Guttler, T, Rymarenko, O, Gorlich, D. | | 登録日 | 2023-08-19 | | 公開日 | 2023-12-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res., 221, 2023
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8Q95
 | | Crystal structure of the SARS-CoV-2 BA.1 RBD with neutralizing-VHHs Ma16B06 and Ma3F05 | | 分子名称: | Nanobody Ma16B06, Nanobody Ma3F05, Spike protein S1 | | 著者 | Aksu, M, Rymarenko, O, Guttler, T, Gorlich, D. | | 登録日 | 2023-08-19 | | 公開日 | 2023-12-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res., 221, 2023
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8Q94
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2ZB2
 | | Human liver glycogen phosphorylase a complexed with glcose and 5-chloro-N-[4-(1,2-dihydroxyethyl)phenyl]-1H-indole-2-carboxamide | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide, ... | | 著者 | Katayama, N, Onda, K. | | 登録日 | 2007-10-15 | | 公開日 | 2008-09-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Synthesis of 5-chloro-N-aryl-1H-indole-2-carboxamide derivatives as inhibitors of human liver glycogen phosphorylase a.
Bioorg.Med.Chem., 16, 2008
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7OLZ
 | | Crystal structure of the SARS-CoV-2 RBD with neutralizing-VHHs Re5D06 and Re9F06 | | 分子名称: | 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, Nanobody Re5D06, Nanobody Re9F06, ... | | 著者 | Aksu, M, Guttler, T, Gorlich, D. | | 登録日 | 2021-05-20 | | 公開日 | 2021-08-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies.
Embo J., 40, 2021
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7ON5
 | | Crystal structure of the SARS-CoV-2 neutralizing nanobody Re5D06 | | 分子名称: | 1,2-ETHANEDIOL, ETHANOL, Nanobody Re5D06 | | 著者 | Aksu, M, Guttler, T, Gorlich, D. | | 登録日 | 2021-05-25 | | 公開日 | 2021-08-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies.
Embo J., 40, 2021
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7NOW
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8CDT
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8CDS
 | | Crystal structure of the xhNup93-Nb4i VHH antibody | | 分子名称: | 1,2-ETHANEDIOL, 5-Nup93 inhibitory VHH antibody, DI(HYDROXYETHYL)ETHER | | 著者 | Guttler, T, Colom, M.S, Gorlich, D. | | 登録日 | 2023-02-01 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodies.
Embo J., 43, 2024
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7NQA
 | | Crystal structure of Nucleoporin-98 nanobody MS98-6 complex solved at 2.2A resolution | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-Nup98 Nanobody MS98-6, Nuclear pore complex protein Nup98-Nup96, ... | | 著者 | Sola-Colom, M, Trakhanov, S, Goerlich, D. | | 登録日 | 2021-03-01 | | 公開日 | 2021-07-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodies.
Embo J., 2024
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8OZB
 | | Crystal structure of Nup35-Nb complex | | 分子名称: | Nucleoporin NUP35, Nup35 nanobody | | 著者 | Srinivasan, V. | | 登録日 | 2023-05-08 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodies.
Embo J., 43, 2024
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7ZOX
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