8CDS

Crystal structure of the xhNup93-Nb4i VHH antibody

Summary for 8CDS

Entry DOI	10.2210/pdb8cds/pdb
Descriptor	5-Nup93 inhibitory VHH antibody, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
Functional Keywords	inhibitory vhh antibody, nanobody, immune system
Biological source	Vicugna pacos (Alpaca)
Total number of polymer chains	1
Total formula weight	14066.65
Authors	Guttler, T.,Colom, M.S.,Gorlich, D. (deposition date: 2023-02-01, release date: 2024-02-21, Last modification date: 2024-06-12)
Primary citation	Sola Colom, M.,Fu, Z.,Gunkel, P.,Guttler, T.,Trakhanov, S.,Srinivasan, V.,Gregor, K.,Pleiner, T.,Gorlich, D. A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodies. Embo J., 43:2198-2232, 2024 Cited by PubMed: 38649536 DOI: 10.1038/s44318-024-00081-w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.53 Å)

Structure validation