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8SLB
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BU of 8slb by Molmil
X-ray structure of CorA N-terminal domain in complex with conformation-specific synthetic antibody C12
分子名称: CHLORIDE ION, Cobalt/magnesium transport protein CorA, sAB C12 Heavy Chain, ...
著者Dominik, P.K, Erramilli, S.K, Reddy, B.G, Kossiakoff, A.A.
登録日2023-04-21
公開日2023-06-07
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.
J.Mol.Biol., 435, 2023
5C8J
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BU of 5c8j by Molmil
A YidC-like protein in the archaeal plasma membrane
分子名称: Antibody fragment, heavy chain, light chain, ...
著者Borowska, M.T, Dominik, P.K, Anghel, S.A, Kossiakoff, A.A, Keenan, R.J.
登録日2015-06-25
公開日2015-09-02
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (3.502 Å)
主引用文献A YidC-like Protein in the Archaeal Plasma Membrane.
Structure, 23, 2015
8U5B
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BU of 8u5b by Molmil
Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain and sFab COP-1
分子名称: COP-1 sFab Heavy Chain, COP-1 sFab Light Chain, Claudin-4, ...
著者Vecchio, A.J.
登録日2023-09-12
公開日2023-09-27
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment.
Commun Biol, 7, 2024
8U4V
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BU of 8u4v by Molmil
Cryo-EM structure of human claudin-4 complex with Clostridium perfringens enterotoxin C-terminal domain, sFab COP-1, and Nanobody
分子名称: Anti-fab nanobody, COP-1 sFab Heavy Chain, COP-1 sFab Light Chain, ...
著者Vecchio, A.J.
登録日2023-09-11
公開日2023-10-25
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment.
Commun Biol, 7, 2024
7KX0
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BU of 7kx0 by Molmil
Crystal structure of the CD27:CD70 co-stimulatory complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, ...
著者Maben, Z, Liu, W, Mosyak, L, Chaparro-Riggers, J.
登録日2020-12-02
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex.
J.Biol.Chem., 297, 2021
3JCF
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BU of 3jcf by Molmil
Cryo-EM structure of the magnesium channel CorA in the closed symmetric magnesium-bound state
分子名称: MAGNESIUM ION, Magnesium transport protein CorA
著者Matthies, D, Perozo, E, Subramaniam, S.
登録日2015-12-11
公開日2016-02-17
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Cell(Cambridge,Mass.), 164, 2016
3JCH
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BU of 3jch by Molmil
Cryo-EM structure of the magnesium channel CorA in the magnesium-free, asymmetric open state II
分子名称: Magnesium transport protein CorA
著者Matthies, D, Perozo, E, Subramaniam, S.
登録日2015-12-11
公開日2016-02-17
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (7.06 Å)
主引用文献Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Cell(Cambridge,Mass.), 164, 2016
3JCG
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Cryo-EM structure of the magnesium channel CorA in the magnesium-free, asymmetric open state I
分子名称: Magnesium transport protein CorA
著者Matthies, D, Perozo, E, Subramaniam, S.
登録日2015-12-11
公開日2016-02-17
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (7.06 Å)
主引用文献Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Cell(Cambridge,Mass.), 164, 2016
5CJO
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BU of 5cjo by Molmil
Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Insulin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FAB Heavy chain with engineered elbow, FAB light chain, ...
著者liang, w.g, bailey, L, tang, w.j.
登録日2015-07-14
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.287 Å)
主引用文献Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 2017
6AZ2
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BU of 6az2 by Molmil
Crystal structure of Asf1-Fab 12E complex
分子名称: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
著者Bailey, L.J, Kossiakoff, A.A.
登録日2017-09-09
公開日2018-01-10
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (2.477 Å)
主引用文献Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 430, 2018
6AYZ
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BU of 6ayz by Molmil
Crystal structure of Asf1-Fab 12E complex
分子名称: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
著者Bailey, L.J, Kossiakoff, A.A.
登録日2017-09-08
公開日2018-01-17
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 430, 2018
7SK4
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BU of 7sk4 by Molmil
Cryo-EM structure of ACKR3 in complex with chemokine N-terminal mutant CXCL12_LRHQ, an intracellular Fab, and an extracellular Fab
分子名称: Atypical chemokine receptor 3, CHOLESTEROL, CID24 Fab heavy chain, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7SK6
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BU of 7sk6 by Molmil
Cryo-EM structure of human ACKR3 in complex with chemokine N-terminal mutant CXCL12_LRHQ and an intracellular Fab
分子名称: Atypical chemokine receptor 3, CID24 Fab heavy chain, CID24 Fab light chain, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7SK9
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BU of 7sk9 by Molmil
Cryo-EM structure of human ACKR3 in complex with a small molecule partial agonist CCX662, and an intracellular Fab
分子名称: (1R)-4-[7-(3-carboxypropoxy)-6-methylquinolin-8-yl]-1-{[2-(4-hydroxypiperidin-1-yl)-1,3-thiazol-4-yl]methyl}-1,4-diazepan-1-ium, Atypical chemokine receptor 3, CHOLESTEROL, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7SK8
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BU of 7sk8 by Molmil
Cryo-EM structure of human ACKR3 in complex with CXCL12, a small molecule partial agonist CCX662, an extracellular Fab, and an intracellular Fab
分子名称: (1R)-4-[7-(3-carboxypropoxy)-6-methylquinolin-8-yl]-1-{[2-(4-hydroxypiperidin-1-yl)-1,3-thiazol-4-yl]methyl}-1,4-diazepan-1-ium, Atypical chemokine receptor 3, CHOLESTEROL, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7SK3
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BU of 7sk3 by Molmil
Cryo-EM structure of ACKR3 in complex with CXCL12, an intracellular Fab, and an extracellular Fab
分子名称: Atypical chemokine receptor 3, CHOLESTEROL, CID24 Fab heavy chain, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7SK5
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BU of 7sk5 by Molmil
Cryo-EM structure of ACKR3 in complex with CXCL12 and an intracellular Fab
分子名称: Anti-Fab nanobody, Atypical chemokine receptor 3, CHOLESTEROL, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7SK7
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BU of 7sk7 by Molmil
Cryo-EM structure of human ACKR3 in complex with CXCL12, a small molecule partial agonist CCX662, and an extracellular Fab
分子名称: (1R)-4-[7-(3-carboxypropoxy)-6-methylquinolin-8-yl]-1-{[2-(4-hydroxypiperidin-1-yl)-1,3-thiazol-4-yl]methyl}-1,4-diazepan-1-ium, Anti-Fab nanobody, Atypical chemokine receptor 3, ...
著者Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G.
登録日2021-10-19
公開日2022-07-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Sci Adv, 8, 2022
7TDM
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BU of 7tdm by Molmil
CryoEM Structure of sFab COP-2 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain
分子名称: COP-2 Fab Heavy chain, COP-2 Fab Light chain, Claudin-4, ...
著者Vecchio, A.J.
登録日2022-01-01
公開日2022-02-09
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
J.Biol.Chem., 298, 2022
7TDN
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BU of 7tdn by Molmil
CryoEM Structure of sFab COP-3 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain
分子名称: COP-3 Fab Heavy chain, COP-3 Fab Light chain, Claudin-4, ...
著者Vecchio, A.J.
登録日2022-01-01
公開日2022-02-09
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
J.Biol.Chem., 298, 2022
6CX0
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Structure of AtTPC1 D376A
分子名称: (1S,3R)-1-(3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid, CALCIUM ION, Two pore calcium channel protein 1
著者Kintzer, A.F, Stroud, R.M.
登録日2018-04-02
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.501 Å)
主引用文献Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1M
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Structure of AtTPC1(DDE) reconstituted in saposin A
分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ...
著者Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M.
登録日2018-07-10
公開日2018-09-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1P
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Structure of AtTPC1(DDE) in state 2
分子名称: CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1
著者Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M.
登録日2018-07-10
公開日2018-09-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1N
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Structure of AtTPC1(DDE) in state 1
分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ...
著者Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M.
登録日2018-07-10
公開日2018-09-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1K
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Structure of AtTPC1(DDE) reconstituted in saposin A with cat06 Fab
分子名称: CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1, ...
著者Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M.
登録日2018-07-10
公開日2018-09-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

 

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