7KX0

Crystal structure of the CD27:CD70 co-stimulatory complex

Summary for 7KX0

Entry DOI	10.2210/pdb7kx0/pdb
Descriptor	CD70 antigen, CD27 antigen, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywords	complex, tnf, costimulation, trimer, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	96511.78
Authors	Maben, Z.,Liu, W.,Mosyak, L.,Chaparro-Riggers, J. (deposition date: 2020-12-02, release date: 2021-09-08, Last modification date: 2023-10-18)
Primary citation	Liu, W.,Maben, Z.,Wang, C.,Lindquist, K.C.,Li, M.,Rayannavar, V.,Lopez Armenta, I.,Nager, A.,Pascua, E.,Dominik, P.K.,Oyen, D.,Wang, H.,Roach, R.C.,Allan, C.M.,Mosyak, L.,Chaparro-Riggers, J. Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex. J.Biol.Chem., 297:101102-101102, 2021 Cited by PubMed: 34419446 DOI: 10.1016/j.jbc.2021.101102 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.69 Å)

Structure validation