3HHR
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1TPK
| CRYSTAL STRUCTURE OF THE KRINGLE-2 DOMAIN OF TISSUE PLASMINOGEN ACTIVATOR AT 2.4-ANGSTROMS RESOLUTION | 分子名称: | CHLORIDE ION, TISSUE PLASMINOGEN ACTIVATOR | 著者 | De vos, A.M, Ultsch, M.H, Kelley, R.F, Padmanabhan, K, Tulinsky, A, Westbrook, M.L, Kossiakoff, A.A. | 登録日 | 1991-09-24 | 公開日 | 1992-07-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution. Biochemistry, 31, 1992
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1A22
| HUMAN GROWTH HORMONE BOUND TO SINGLE RECEPTOR | 分子名称: | GROWTH HORMONE, GROWTH HORMONE RECEPTOR | 著者 | De Vos, A.M, Ultsch, M. | 登録日 | 1998-01-15 | 公開日 | 1998-04-29 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. J.Mol.Biol., 277, 1998
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1F6F
| CRYSTAL STRUCTURE OF THE TERNARY COMPLEX BETWEEN OVINE PLACENTAL LACTOGEN AND THE EXTRACELLULAR DOMAIN OF THE RAT PROLACTIN RECEPTOR | 分子名称: | PLACENTAL LACTOGEN, PROLACTIN RECEPTOR | 著者 | Elkins, P.A, Christinger, H.W, Sandowski, Y, Sakal, E, Gertler, A, De Vos, A.M, Kossiakoff, A.A. | 登録日 | 2000-06-21 | 公開日 | 2000-07-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor. Nat.Struct.Biol., 7, 2000
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1FLT
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1WWB
| LIGAND BINDING DOMAIN OF HUMAN TRKB RECEPTOR | 分子名称: | PROTEIN (Brain Derived Neurotrophic Factor Receptor TrkB) | 著者 | Wiesmann, C, Ultsch, M.H, Bass, S.H, De Vos, A.M. | 登録日 | 1999-05-03 | 公開日 | 1999-07-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC. J.Mol.Biol., 290, 1999
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1WWW
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2VPF
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2HFT
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1S78
| Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, ... | 著者 | Franklin, M.C, Carey, K.D, Vajdos, F.F, Leahy, D.J, de Vos, A.M, Sliwkowski, M.X. | 登録日 | 2004-01-29 | 公開日 | 2004-04-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex. Cancer Cell, 5, 2004
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1QTY
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1RV6
| Crystal Structure of PlGF in Complex with Domain 2 of VEGFR1 | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLT1 protein, placenta growth factor (PlGF) | 著者 | Christinger, H.W, Fuh, G, de Vos, A.M, Wiesmann, C. | 登録日 | 2003-12-12 | 公開日 | 2004-01-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | The crystal structure of placental growth factor in complex with domain 2 of vascular endothelial growth factor receptor-1. J.Biol.Chem., 279, 2004
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1VPF
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1WWC
| NT3 BINDING DOMAIN OF HUMAN TRKC RECEPTOR | 分子名称: | PROTEIN (NT-3 GROWTH FACTOR RECEPTOR TRKC) | 著者 | Ultsch, M.H, Wiesmann, C, Simmons, L.C, Henrich, J, Yang, M, Reilly, D, Bass, S.H, De Vos, A.M. | 登録日 | 1999-04-30 | 公開日 | 1999-07-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC. J.Mol.Biol., 290, 1999
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1WWA
| NGF BINDING DOMAIN OF HUMAN TRKA RECEPTOR | 分子名称: | PROTEIN (NERVE GROWTH FACTOR RECEPTOR TRKA) | 著者 | Wiesmann, C, Ultsch, M.H, Bass, S.H, De Vos, A.M. | 登録日 | 1999-04-29 | 公開日 | 1999-07-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC. J.Mol.Biol., 290, 1999
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2PF2
| THE CA+2 ION AND MEMBRANE BINDING STRUCTURE OF THE GLA DOMAIN OF CA-PROTHROMBIN FRAGMENT 1 | 分子名称: | CALCIUM ION, PROTHROMBIN FRAGMENT 1 | 著者 | Soriano-Garcia, M, Padmanabhan, K, De vos, A.M, Tulinsky, A. | 登録日 | 1991-12-08 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Ca2+ ion and membrane binding structure of the Gla domain of Ca-prothrombin fragment 1. Biochemistry, 31, 1992
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1M1L
| Human Suppressor of Fused (N-terminal domain) | 分子名称: | Suppressor of Fused | 著者 | Merchant, M, Vajdos, F.F, Ultsch, M, Maun, H.R, Wendt, U, Cannon, J, Lazarus, R.A, de Vos, A.M, de Sauvage, F.J. | 登録日 | 2002-06-19 | 公開日 | 2004-02-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Suppressor of fused regulates Gli activity through a dual binding mechanism Mol.Cell.Biol., 24, 2004
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1OQO
| Complex between G0 version of an Fc bound to a minimized version of Protein A called Mini-Z | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Minimized version of Protein A (Z34C), ... | 著者 | Raju, T.S, Mulkerrin, M.G, Parker, M, De Vos, A.M, Gazzano-Santoro, H, Totpal, K, Ultsch, M.H. | 登録日 | 2003-03-10 | 公開日 | 2003-03-20 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Impact of Fc Glycans on The Effector
Functions Vary with the Antibody
mechanism of Action To be Published
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1QSV
| THE VEGF-BINDING DOMAIN OF FLT-1, 20 NMR STRUCTURES | 分子名称: | VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 | 著者 | Starovasnik, M.A, Christinger, H.W, Wiesmann, C, Champe, M.A, de Vos, A.M, Skelton, N.J. | 登録日 | 1999-06-23 | 公開日 | 1999-11-10 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the VEGF-binding domain of Flt-1: comparison of its free and bound states. J.Mol.Biol., 293, 1999
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1OQX
| G-2 glycovariant of human IgG Fc bound to minimized version of Protein A called Z34C | 分子名称: | Protein A Z34C, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Raju, T.S, Mulkerrin, M.G, Parker, M, De Vos, A.M, Gazzano-Santoro, H, Totpal, K, Ultsch, M.H. | 登録日 | 2003-03-11 | 公開日 | 2003-03-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Impact of Fc Glycans on The Effector Functions Vary
with the Antibody mechanism of Action To be Published
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1QSZ
| THE VEGF-BINDING DOMAIN OF FLT-1 (MINIMIZED MEAN) | 分子名称: | VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 | 著者 | Starovasnik, M.A, Christinger, H.W, Wiesmann, C, Champe, M.A, de Vos, A.M, Skelton, N.J. | 登録日 | 1999-06-24 | 公開日 | 1999-11-10 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the VEGF-binding domain of Flt-1: comparison of its free and bound states. J.Mol.Biol., 293, 1999
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1RJ8
| The crystal structure of TNF family member EDA-A2 | 分子名称: | ectodysplasin-A isoform EDA-A2 | 著者 | Hymowitz, S.G, Compaan, D.M, Yan, M, Ackerly, H, Dixit, V.M, Starovasnik, M.A, de Vos, A.M. | 登録日 | 2003-11-18 | 公開日 | 2003-12-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | The Crystal Structure of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity STRUCTURE, 11, 2003
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1RJ7
| Crystal structure of EDA-A1 | 分子名称: | Ectodysplasin A | 著者 | Hymowitz, S.G, Compaan, D.M, Yan, M, Ackerly, H, Dixit, V.M, Starovasnik, M.A, de Vos, A.M. | 登録日 | 2003-11-18 | 公開日 | 2003-12-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity. Structure, 11, 2003
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1VPP
| COMPLEX BETWEEN VEGF AND A RECEPTOR BLOCKING PEPTIDE | 分子名称: | PROTEIN (PEPTIDE V108), PROTEIN (VASCULAR ENDOTHELIAL GROWTH FACTOR) | 著者 | Wiesmann, C, Christinger, H.W, Cochran, A.G, Cunningham, B.C, Fairbrother, W.J, Keenan, C.J, Meng, G, de Vos, A.M. | 登録日 | 1998-10-09 | 公開日 | 1999-02-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the complex between VEGF and a receptor-blocking peptide. Biochemistry, 37, 1998
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1HUW
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