1RJ8

The crystal structure of TNF family member EDA-A2

Summary for 1RJ8

• Entry DOI: 10.2210/pdb1rj8/pdb
• Related: 1RJ7
• Descriptor: ectodysplasin-A isoform EDA-A2 (2 entities in total)
• Functional Keywords: tnf domain, jelly roll, splice variant, trimer, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane ; Single-pass type II membrane protein . Ectodysplasin-A, secreted form: Secreted : Q92838
• Total number of polymer chains: 6
• Total formula weight: 107726.32

Authors

Hymowitz, S.G.,Compaan, D.M.,Yan, M.,Ackerly, H.,Dixit, V.M.,Starovasnik, M.A.,de Vos, A.M. (deposition date: 2003-11-18, release date: 2003-12-09, Last modification date: 2024-04-03)

• Primary citation: Hymowitz, S.G.,Compaan, D.M.,Yan, M.,Ackerly, H.,Dixit, V.M.,Starovasnik, M.A.,de Vos, A.M.; The Crystal Structure of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity; STRUCTURE, 11:1513-1520, 2003; PubMed: 14656435; DOI: 10.1016/j.str.2003.11.009

Experimental method

X-RAY DIFFRACTION (2.23 Å)