1M1L

Human Suppressor of Fused (N-terminal domain)

Summary for 1M1L

DescriptorSuppressor of Fused (2 entities in total)
Functional Keywordsgene regulation, hedgehog signaling, signal transduction, fused, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q9UMX1
Total number of polymer chains4
Total molecular weight106370.92
Authors
Merchant, M.,Vajdos, F.F.,Ultsch, M.,Maun, H.R.,Wendt, U.,Cannon, J.,Lazarus, R.A.,de Vos, A.M.,de Sauvage, F.J. (deposition date: 2002-06-19, release date: 2004-02-03, Last modification date: 2011-07-13)
Primary citation
Merchant, M.,Vajdos, F.F.,Ultsch, M.,Maun, H.R.,Wendt, U.,Cannon, J.,Desmarais, W.,Lazarus, R.A.,de Vos, A.M.,de Sauvage, F.J.
Suppressor of fused regulates Gli activity through a dual binding mechanism
Mol.Cell.Biol., 24:8627-8641, 2004
PubMed: 15367681 (PDB entries with the same primary citation)
DOI: 10.1128/MCB.24.19.8627-8641.2004
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.65 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.209171.2%2.6%2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1m1l
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Molmil generated image of 1m1l
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Molmil generated image of 1m1l
rotated about y axis by 90°