1OQO

Complex between G0 version of an Fc bound to a minimized version of Protein A called Mini-Z

Summary for 1OQO
Related1L6X
Descriptorimmunoglobulin gamma-1 heavy chain constant region, Minimized version of Protein A (Z34C), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywordsantibody, glycosylation, oligosaccharides, igg, fc fragment, z34c, protein a, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight59258.21
Authors
Raju, T.S.,Mulkerrin, M.G.,Parker, M.,De Vos, A.M.,Gazzano-Santoro, H.,Totpal, K.,Ultsch, M.H. (deposition date: 2003-03-10, release date: 2003-03-20, Last modification date: 2020-12-16)
Primary citationDe Vos, A.M.,Gazzano-Santoro, H.,Mulkerrin, M.G.,Parker, M.,Raju, T.S.,Totpal, K.,Ultsch, M.H.
Impact of Fc Glycans on The Effector Functions Vary with the Antibody mechanism of Action
To be Published,
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation
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PDB entries from 2021-06-16