7NX4
 
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7NWZ
 | | ALK:ALKAL2 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK and LTK ligand 2, ALK tyrosine kinase receptor | | 著者 | De Munck, S, Savvides, S.N. | | 登録日 | 2021-03-17 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (4.17 Å) | | 主引用文献 | Structural basis of cytokine-mediated activation of ALK family receptors.
Nature, 600, 2021
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7NX2
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7NX0
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7NX1
 | | TG domain of LTK | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Leukocyte tyrosine kinase receptor, TERBIUM(III) ION | | 著者 | De Munck, S, Savvides, S.N. | | 登録日 | 2021-03-17 | | 公開日 | 2021-10-27 | | 最終更新日 | 2021-12-15 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structural basis of cytokine-mediated activation of ALK family receptors.
Nature, 600, 2021
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7NX3
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4WRL
 | | Structure of the human CSF-1:CSF-1R complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage colony-stimulating factor 1, Macrophage colony-stimulating factor 1 receptor, ... | | 著者 | Felix, J, De Munck, S, Elegheert, J, Savvides, S.N. | | 登録日 | 2014-10-24 | | 公開日 | 2015-08-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | | 主引用文献 | Structure and Assembly Mechanism of the Signaling Complex Mediated by Human CSF-1.
Structure, 23, 2015
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4WRM
 | | Structure of the human CSF-1:CSF-1R complex | | 分子名称: | Macrophage colony-stimulating factor 1, Macrophage colony-stimulating factor 1 receptor | | 著者 | Felix, J, De Munck, S, Elegheert, J, Savvides, S.N. | | 登録日 | 2014-10-24 | | 公開日 | 2015-08-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (6.853 Å) | | 主引用文献 | Structure and Assembly Mechanism of the Signaling Complex Mediated by Human CSF-1.
Structure, 23, 2015
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6YIG
 | | Crystal structure of the N-terminal EF-hand domain of Arabidopsis thaliana AtEH1/Pan1 | | 分子名称: | CALCIUM ION, Calcium-binding EF hand family protein, SODIUM ION | | 著者 | Yperman, K, Merceron, R, De Munck, S, Bloch, Y, Savvides, S.N, Pleskot, R, Van Damme, D. | | 登録日 | 2020-04-01 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Nat Commun, 12, 2021
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6YT1
 | | Mtb TMK crystal structure in complex with compound 26 | | 分子名称: | 2-ethyl-~{N}-[[4-[4-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]piperidin-1-yl]phenyl]methyl]-1,2,3,5,6,7,8,8~{a}-octahydroimidazo[1,2-a]pyridine-3-carboxamide, CITRIC ACID, Thymidylate kinase | | 著者 | Merceron, R, De Munck, S, Jian, Y, Munier-Lehmann, H, Van Calenbergh, S, Savvides, S.N. | | 登録日 | 2020-04-23 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents.
Eur.J.Med.Chem., 206, 2020
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7R3N
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6ZR7
 | | X-ray structure of human Dscam Ig7-Ig9 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Down syndrome cell adhesion molecule, ... | | 著者 | Kozak, S, Bento, I, Meijers, R. | | 登録日 | 2020-07-11 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis.
Acta Crystallogr D Struct Biol, 76, 2020
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6E4L
 | | The structure of the N-terminal domain of human clathrin heavy chain 1 (nTD) in complex with ES9 | | 分子名称: | 1,2-ETHANEDIOL, 5-bromo-N-(4-nitrophenyl)thiophene-2-sulfonamide, ACETATE ION, ... | | 著者 | Dejonghe, W, Sharma, I, Denoo, B, Munck, S.D, Bulut, H, Mylle, E, Vasileva, M, Lu, Q, Savatin, D.V, Mishev, K, Nerinckx, W, Staes, A, Drozdzecki, A, Audenaert, D, Madder, A, Friml, J, Damme, D.V, Gevaert, K, Haucke, V, Savvides, S, Winne, J, Russinova, E. | | 登録日 | 2018-07-17 | | 公開日 | 2019-04-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Disruption of endocytosis through chemical inhibition of clathrin heavy chain function.
Nat.Chem.Biol., 15, 2019
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6SFF
 | | mouse Interleukin-12 subunit beta - p80 homodimer in space group I41 | | 分子名称: | CHLORIDE ION, Interleukin-12 subunit beta, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Bloch, Y, Savvides, S.N. | | 登録日 | 2019-08-01 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis.
Acta Crystallogr D Struct Biol, 76, 2020
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6YEU
 | | Second EH domain of AtEH1/Pan1 | | 分子名称: | CALCIUM ION, Calcium-binding EF hand family protein | | 著者 | Yperman, K, Papageorgiou, A, Evangelidis, T, Van Damme, D, Tripsianes, K. | | 登録日 | 2020-03-25 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Nat Commun, 12, 2021
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6YET
 | | Second EH domain of AtEH1/Pan1 | | 分子名称: | CALCIUM ION, Calcium-binding EF hand family protein | | 著者 | Yperman, K, Papageorgiou, A, Evangelidis, T, Van Damme, D, Tripsianes, K. | | 登録日 | 2020-03-25 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Nat Commun, 12, 2021
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7PUR
 | | mouse Interleukin-12 subunit beta - p80 homodimer in space group P21 crystal form 2 | | 分子名称: | Interleukin-12 subunit beta, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Bloch, Y, Savvides, S.N. | | 登録日 | 2021-09-30 | | 公開日 | 2021-11-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Around she goes: the structure of mouse Interleukin-12 p80
To Be Published
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5D28
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5D22
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