6SFF
mouse Interleukin-12 subunit beta - p80 homodimer in space group I41
Summary for 6SFF
| Entry DOI | 10.2210/pdb6sff/pdb |
| Descriptor | Interleukin-12 subunit beta, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | homodimer, antagonist, fibronectin, secreted glycoprotein, cytokine |
| Biological source | Mus musculus (House mouse) |
| Total number of polymer chains | 1 |
| Total formula weight | 40507.01 |
| Authors | Bloch, Y.,Savvides, S.N. (deposition date: 2019-08-01, release date: 2020-08-26, Last modification date: 2024-01-24) |
| Primary citation | Kozak, S.,Bloch, Y.,De Munck, S.,Mikula, A.,Bento, I.,Savvides, S.N.,Meijers, R. Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis. Acta Crystallogr D Struct Biol, 76:1244-1255, 2020 Cited by PubMed: 33263330DOI: 10.1107/S2059798320013753 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report
