5D22

Structure of ovine granulocyte-macrophage colony-stimulating factor

Summary for 5D22

Entry DOI	10.2210/pdb5d22/pdb
Descriptor	Granulocyte-macrophage colony-stimulating factor, ACETATE ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	signaling protein, recombinant proteins, cytokine immunology, cytokine
Biological source	Ovis aries (Sheep)
Cellular location	Secreted: P28773
Total number of polymer chains	2
Total formula weight	29032.93
Authors	Felix, J.,Savvides, S.N. (deposition date: 2015-08-05, release date: 2016-11-16, Last modification date: 2024-01-10)
Primary citation	Felix, J.,Kandiah, E.,De Munck, S.,Bloch, Y.,van Zundert, G.C.,Pauwels, K.,Dansercoer, A.,Novanska, K.,Read, R.J.,Bonvin, A.M.,Vergauwen, B.,Verstraete, K.,Gutsche, I.,Savvides, S.N. Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF. Nat Commun, 7:13228-13228, 2016 Cited by PubMed: 27819269 DOI: 10.1038/ncomms13228 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.994 Å)

Structure validation