7EZC
| Adenosine A2a receptor mutant-I92N | 分子名称: | 6-(2,2-diphenylethylamino)-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]-N-[2-[(1-pyridin-2-ylpiperidin-4-yl)carbamoylamino]ethyl]purine-2-carboxamide, Adenosine receptor A2a,Soluble cytochrome b562 | 著者 | Cui, M, Zhou, Q, Yao, D, Zhao, S, Song, G. | 登録日 | 2021-06-01 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Crystal structure of a constitutive active mutant of adenosine A 2A receptor. Iucrj, 9, 2022
|
|
7N6B
| |
7MXO
| CryoEM structure of human NKCC1 | 分子名称: | CHLORIDE ION, POTASSIUM ION, Solute carrier family 12 member 2 | 著者 | Moseng, M.A. | 登録日 | 2021-05-19 | 公開日 | 2022-09-28 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
|
|
7N3N
| CryoEM structure of human NKCC1 state Fu-I | 分子名称: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | 著者 | Moseng, M.A. | 登録日 | 2021-06-01 | 公開日 | 2022-09-28 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
|
|
4XZZ
| Structure of Helicobacter pylori Csd6 in the ligand-free state | 分子名称: | Conserved hypothetical secreted protein, GLYCEROL | 著者 | Kim, H.S, Im, H.N, Yoon, H.J, Suh, S.W. | 登録日 | 2015-02-05 | 公開日 | 2015-09-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | The Cell Shape-determining Csd6 Protein from Helicobacter pylori Constitutes a New Family of l,d-Carboxypeptidase J.Biol.Chem., 290, 2015
|
|
8XAI
| |
4Y4V
| Structure of Helicobacter pylori Csd6 in the D-Ala-bound state | 分子名称: | Conserved hypothetical secreted protein, D-ALANINE, GLYCEROL | 著者 | Kim, H.S, Im, H.N, Yoon, H.J, Suh, S.W. | 登録日 | 2015-02-11 | 公開日 | 2015-09-02 | 最終更新日 | 2022-03-23 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | The Cell Shape-determining Csd6 Protein from Helicobacter pylori Constitutes a New Family of l,d-Carboxypeptidase J.Biol.Chem., 290, 2015
|
|
7SFL
| Human NKCC1 state Fu-II | 分子名称: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | 著者 | Moseng, M.A. | 登録日 | 2021-10-04 | 公開日 | 2022-09-28 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | 主引用文献 | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
|
|
7SMP
| CryoEM structure of NKCC1 Bu-I | 分子名称: | 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid, POTASSIUM ION, Solute carrier family 12 member 2 | 著者 | Moseng, M.A. | 登録日 | 2021-10-26 | 公開日 | 2022-09-28 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
|
|
8F4R
| Gentamicin bound aminoglycoside efflux pump AcrD | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, Efflux pump membrane transporter | 著者 | Zhang, Z. | 登録日 | 2022-11-11 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity. Mbio, 14, 2023
|
|
8F56
| |
8F4N
| Dimer of aminoglycoside efflux pump AcrD | 分子名称: | Efflux pump membrane transporter | 著者 | Zhang, Z. | 登録日 | 2022-11-11 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity. Mbio, 14, 2023
|
|
8F3E
| Trimer of aminoglycoside efflux pump AcrD | 分子名称: | Efflux pump membrane transporter | 著者 | Zhang, Z. | 登録日 | 2022-11-10 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity. Mbio, 14, 2023
|
|
6CZQ
| |
7XDQ
| Crystal structure of a glucosylglycerol phosphorylase mutant from Marinobacter adhaerens | 分子名称: | Glucosylglycerol phosphorylase, LITHIUM ION, beta-D-glucopyranose | 著者 | Wei, H.L, Li, Q, Yang, J.G, Liu, W.D, Sun, Y.X. | 登録日 | 2022-03-28 | 公開日 | 2023-02-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | Protein Engineering of Glucosylglycerol Phosphorylase Facilitating Efficient and Highly Regio- and Stereoselective Glycosylation of Polyols in a Synthetic System. Acs Catalysis, 2022
|
|
7XDR
| Crystal structure of a glucosylglycerol phosphorylase from Marinobacter adhaerens | 分子名称: | Glucosylglycerol phosphorylase | 著者 | Wei, H.L, Li, Q, Yang, J.G, Liu, W.D, Sun, Y.X. | 登録日 | 2022-03-28 | 公開日 | 2023-02-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Protein Engineering of Glucosylglycerol Phosphorylase Facilitating Efficient and Highly Regio- and Stereoselective Glycosylation of Polyols in a Synthetic System. Acs Catalysis, 2022
|
|
8VTT
| Meis1 homeobox domain bound to neomycin fragment | 分子名称: | Homeobox protein Meis1, RIBOSTAMYCIN, SULFATE ION | 著者 | Tomchick, D.R, Ahmed, M.S, Nguyen, N.U.N, Sadek, H.A. | 登録日 | 2024-01-27 | 公開日 | 2024-02-14 | 最終更新日 | 2024-09-11 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Identification of FDA-approved drugs that induce heart regeneration in mammals. Nat Cardiovasc Res, 3, 2024
|
|
8VTS
| Meis1 homeobox domain bound to paromomycin fragment | 分子名称: | 1,2-ETHANEDIOL, Homeobox protein Meis1, ISOPROPYL ALCOHOL, ... | 著者 | Tomchick, D.R, Ahmed, M.S, Nguyen, N.U.N. | 登録日 | 2024-01-27 | 公開日 | 2024-02-14 | 最終更新日 | 2024-09-11 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Identification of FDA-approved drugs that induce heart regeneration in mammals. Nat Cardiovasc Res, 3, 2024
|
|
6ALE
| A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model | 分子名称: | (3E)-6,7-dichloro-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-one, CALCIUM ION, Calmodulin-2, ... | 著者 | Nam, Y.W, Zhang, M. | 登録日 | 2017-08-07 | 公開日 | 2018-08-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A V-to-F substitution in SK2 channels causes Ca2+hypersensitivity and improves locomotion in a C. elegans ALS model. Sci Rep, 8, 2018
|
|
8STE
| Cryo-EM structure of NKCC1 Fu_CTD | 分子名称: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | 著者 | Moseng, M.A. | 登録日 | 2023-05-10 | 公開日 | 2023-05-17 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | 主引用文献 | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8, 2022
|
|
5WBX
| |
5WC5
| |
6KZQ
| structure of PTP-MEG2 and NSF-pY83 peptide complex | 分子名称: | NSF-pY83 peptide, Tyrosine-protein phosphatase non-receptor type 9 | 著者 | Xu, Y.F, Chen, X, Yu, X, Sun, J.P. | 登録日 | 2019-09-25 | 公開日 | 2020-09-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Rep., 22, 2021
|
|
6L03
| structure of PTP-MEG2 and MUNC18-1-pY145 peptide complex | 分子名称: | Tyrosine-protein phosphatase non-receptor type 9, stxbp1-pY145 peptide | 著者 | Xu, Y.F, Chen, X, Yu, X, Sun, J.P. | 登録日 | 2019-09-25 | 公開日 | 2020-09-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.084 Å) | 主引用文献 | PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Rep., 22, 2021
|
|
4QNH
| Calcium-calmodulin (T79D) complexed with the calmodulin binding domain from a small conductance potassium channel SK2-a | 分子名称: | CALCIUM ION, Calmodulin, SULFATE ION, ... | 著者 | Zhang, M, Pascal, J.M, Logothetis, D.E, Zhang, J.F. | 登録日 | 2014-06-17 | 公開日 | 2014-08-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex. Nat.Chem.Biol., 10, 2014
|
|