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4QUN
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BU of 4qun by Molmil
Crystal structure of the PTPN3 (PTPH1) catalytic domain C842S mutant
分子名称: GLYCEROL, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.E, Meng, T.C, Wang, A.H.J.
登録日2014-07-11
公開日2014-12-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Reciprocal allosteric regulation of p38 gamma and PTPN3 involves a PDZ domain-modulated complex formation.
Sci.Signal., 7, 2014
4QUM
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BU of 4qum by Molmil
Crystal structure of PTPN3 (PTPH1) in complex with a dually phosphorylated MAPK12 peptide
分子名称: Mitogen-activated protein kinase 12, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.E, Meng, T.C, Wang, A.H.J.
登録日2014-07-10
公開日2014-12-10
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.516 Å)
主引用文献Reciprocal allosteric regulation of p38 gamma and PTPN3 involves a PDZ domain-modulated complex formation.
Sci.Signal., 7, 2014
7CGA
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Crystal structure of human unphosphorylated p38gamma
分子名称: Mitogen-activated protein kinase 12
著者Lee, C.C, Hsu, S.F, Chen, K.E, Wang, A.H.J, Meng, T.C.
登録日2020-06-30
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural basis for allosteric regulation of protein tyrosine phosphatase PTPN3 by unphosphorylated MAP kinase p38g
To be published
8FUD
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BU of 8fud by Molmil
Crystal structure of Vps29 in complex with Chaetomium thermophilum Vps5 (71 to 80)
分子名称: DIMETHYL SULFOXIDE, GLYCEROL, PHOSPHATE ION, ...
著者Chen, K.-E, Collins, B.
登録日2023-01-17
公開日2024-07-24
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer
Biorxiv, 2024
4RH5
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BU of 4rh5 by Molmil
Crystal structure of PTPN3 (PTPH1) in complex with Eps15 pTyr849 peptide
分子名称: Epidermal growth factor receptor substrate 15, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.-E, Meng, T.C, Wang, A.H.-J.
登録日2014-10-01
公開日2015-03-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23, 2015
4RH9
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BU of 4rh9 by Molmil
Crystal structure of PTPN3 (PTPH1) H812F, M883G mutant in complex with Eps15 pTyr849 peptide
分子名称: Epidermal growth factor receptor substrate 15, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.-E, Meng, T.C, Wang, A.H.-J.
登録日2014-10-01
公開日2015-03-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23, 2015
4RHG
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Crystal structure of PTPN3 (PTPH1) D811E, C842S mutant in complex with Eps15 pTyr849 peptide
分子名称: Epidermal growth factor receptor substrate 15, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.-E, Meng, T.C, Wang, A.H.-J.
登録日2014-10-02
公開日2015-03-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.581 Å)
主引用文献Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23, 2015
4RI4
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BU of 4ri4 by Molmil
Crystal structure of PTPN3 (PTPH1) Y676I mutant in complex with vanadate
分子名称: Tyrosine-protein phosphatase non-receptor type 3, VANADATE ION
著者Chen, K.-E, Meng, T.C, Wang, A.H.-J.
登録日2014-10-05
公開日2015-03-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.596 Å)
主引用文献Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23, 2015
4RI5
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Crystal structure of PTPN3 (PTPH1) D811E mutant in complex with metavanadate
分子名称: GLYCEROL, Tyrosine-protein phosphatase non-receptor type 3, oxido(dioxo)vanadium
著者Chen, K.-E, Meng, T.C, Wang, A.H.-J.
登録日2014-10-05
公開日2015-03-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23, 2015
4S0G
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Crystal structure of PTPN3 (PTPH1) in complex with Eps15 pTyr849 P850V peptide
分子名称: Peptide from Epidermal growth factor receptor substrate 15, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.-E, Meng, T.C, Wang, A.H.-J.
登録日2014-12-31
公開日2015-03-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.723 Å)
主引用文献Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23, 2015
6XS7
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BU of 6xs7 by Molmil
Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-D2
分子名称: 48V-DTY-THR-THR-ILE-TYR-TRP-THR-PRO-LEU-GLY-THR-PHE-PRO-ARG-ILE-ARG, FORMIC ACID, GLYCEROL, ...
著者Chen, K.-E, Guo, Q, Collins, B.M.
登録日2020-07-15
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6XSA
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Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-L2
分子名称: 48V-TYR-LEU-PRO-THR-ILE-THR-GLY-VAL-GLY-HIS-LEU-TRP-HIS-PRO-LEU, SULFATE ION, Vacuolar protein sorting-associated protein 29
著者Chen, K.-E, Guo, Q, Collins, B.M.
登録日2020-07-15
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6XS5
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Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-D1
分子名称: 48V-DTY-ILE-ILE-ASP-THR-PRO-LEU-GLY-VAL-PHE-LEU-SER-SER-LEU-LYS-ARG, FORMIC ACID, GLYCEROL, ...
著者Chen, K.-E, Guo, Q, Collins, B.M.
登録日2020-07-15
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6XS8
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BU of 6xs8 by Molmil
Crystal structure of Chaetomium thermophilum Vps29 complexed with RaPID-derived cyclic peptide RT-D3
分子名称: 48V-DTY-GLY-TYR-ASP-PRO-LEU-GLY-LEU-LYS-TYR-PHE-ALA, Vacuolar protein sorting-associated protein 29
著者Chen, K.-E, Guo, Q, Collins, B.M.
登録日2020-07-15
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95009851 Å)
主引用文献De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6XS9
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BU of 6xs9 by Molmil
Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-L1
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 48V-TYR-ILE-LYS-THR-PRO-LEU-GLY-THR-PHE-PRO-ASN-ARG-HIS-GLY, GLYCEROL, ...
著者Chen, K.-E, Guo, Q, Collins, B.M.
登録日2020-07-15
公開日2021-07-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
3UX3
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BU of 3ux3 by Molmil
Crystal Structure of Domain-Swapped Fam96a minor dimer
分子名称: ACETATE ION, MIP18 family protein FAM96A, ZINC ION
著者Chen, K.-E, Kobe, B, Martin, J.L.
登録日2011-12-03
公開日2012-05-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer.
Acta Crystallogr.,Sect.D, 68, 2012
3UX2
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Crystal Structure of Domain-Swapped Fam96a Major dimer
分子名称: MIP18 family protein FAM96A
著者Chen, K.-E, Kobe, B, Martin, J.L.
登録日2011-12-03
公開日2012-05-30
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer.
Acta Crystallogr.,Sect.D, 68, 2012
6BTZ
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BU of 6btz by Molmil
Crystal structure of the PI3KC2alpha C2 domain in space group C121
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, ...
著者Chen, K.-E, Collins, B.M.
登録日2017-12-08
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
6BTY
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BU of 6bty by Molmil
Crystal structure of the PI3KC2alpha C2 domain in space group P41212
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
著者Chen, K.-E, Collins, B.M.
登録日2017-12-08
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.678 Å)
主引用文献Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
6BU0
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BU of 6bu0 by Molmil
Crystal structure of the PI3KC2alpha C2 domain in complex with IP6
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, FORMIC ACID, INOSITOL HEXAKISPHOSPHATE, ...
著者Chen, K.-E, Collins, B.M.
登録日2017-12-08
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.427 Å)
主引用文献Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
6BUB
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BU of 6bub by Molmil
Crystal structure of the PI3KC2alpha PX domain in space group P432
分子名称: GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, SULFATE ION
著者Chen, K.-E, Collins, B.M.
登録日2017-12-09
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
4DWN
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BU of 4dwn by Molmil
Crystal Structure of Human BinCARD CARD
分子名称: Bcl10-interacting CARD protein, SULFATE ION
著者Chen, K.-E, Kobe, B, Martin, J.L.
登録日2012-02-26
公開日2013-02-06
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.581 Å)
主引用文献The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized.
Acta Crystallogr.,Sect.D, 69, 2013
4FH0
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Crystal Structure of Human BinCARD CARD, double mutant F16M/L66M SeMet form
分子名称: Bcl10-interacting CARD protein, SULFATE ION
著者Chen, K.-E, Kobe, B, Martin, J.L.
登録日2012-06-05
公開日2013-02-06
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized.
Acta Crystallogr.,Sect.D, 69, 2013
8F2R
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Human CCC complex
分子名称: COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ...
著者Healy, M.D, McNally, K.E, Butkovic, R, Chilton, M, Kato, K, Sacharz, J, McConville, C, Moody, E.R.R, Shaw, S, Planelles-Herrero, V.J, Kadapalakere, S.Y, Ross, J, Borucu, U, Palmer, C.S, Chen, K, Croll, T.I, Hall, R.J, Caruana, N.J, Ghai, R, Nguyen, T.H.D, Heesom, K.J, Saitoh, S, Berger, I, Berger-Schaffitzel, C, Williams, T.A, Stroud, D.A, Derivery, E, Collins, B.M, Cullen, P.J.
登録日2022-11-08
公開日2023-05-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
8F2U
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Human CCC complex
分子名称: COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ...
著者Healy, M.D, McNally, K.E, Butkovic, R, Chilton, M, Kato, K, Sacharz, J, McConville, C, Moody, E.R.R, Shaw, S, Planelles-Herrero, V.J, Kadapalakere, S.Y, Ross, J, Borucu, U, Palmer, C.S, Chen, K, Croll, T.I, Hall, R.J, Caruana, N.J, Ghai, R, Nguyen, T.H.D, Heesom, K.J, Saitoh, S, Berger, I, Berger-Schaffitzel, C, Williams, T.A, Stroud, D.A, Derivery, E, Collins, B.M, Cullen, P.J.
登録日2022-11-08
公開日2023-05-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023

 

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