Crystal structure of PTPN3 (PTPH1) D811E mutant in complex with metavanadate

Summary for 4RI5

Related4RHG 4RI4 4RH5 4RH9
DescriptorTyrosine-protein phosphatase non-receptor type 3, GLYCEROL, oxido(dioxo)vanadium, ... (4 entities in total)
Functional Keywordsalpha beta, hydrolase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight70305.59
Chen, K.-E.,Meng, T.C.,Wang, A.H.-J. (deposition date: 2014-10-05, release date: 2015-03-11, Last modification date: 2018-07-18)
Primary citation
Chen, K.E.,Li, M.Y.,Chou, C.C.,Ho, M.R.,Chen, G.C.,Meng, T.C.,Wang, A.H.
Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23:653-664, 2015
PubMed: 25728925 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2015.01.017
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.17530.5%1.4%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-08-12