6BTY

Crystal structure of the PI3KC2alpha C2 domain in space group P41212

Summary for 6BTY

• Entry DOI: 10.2210/pdb6bty/pdb
• Related: 2B3R
• Descriptor: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE (3 entities in total)
• Functional Keywords: c2 domain, lipid binding, phosphoinositide, pi3-kinase, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 30152.67

Authors

Chen, K.-E.,Collins, B.M. (deposition date: 2017-12-08, release date: 2018-10-17, Last modification date: 2023-10-04)

• Primary citation: Chen, K.E.,Tillu, V.A.,Chandra, M.,Collins, B.M.; Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.; Structure, 26:1612-, 2018; PubMed: 30293811; DOI: 10.1016/j.str.2018.08.010

Experimental method

X-RAY DIFFRACTION (1.678 Å)