3R4U
 
 | | Cell entry of botulinum neurotoxin type C is dependent upon interaction with two ganglioside molecules | | 分子名称: | Botulinum neurotoxin type C1 | | 著者 | Strotmeier, J, Gu, S, Jutzi, S, Mahrhold, S, Zhou, J, Pich, A, Bigalke, H, Rummel, A, Jin, R, Binz, T. | | 登録日 | 2011-03-17 | | 公開日 | 2011-06-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Mol.Microbiol., 81, 2011
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3R4S
 | | Cell entry of botulinum neurotoxin type C is dependent upon interaction with two ganglioside molecules | | 分子名称: | Botulinum neurotoxin type C1, N-acetyl-alpha-neuraminic acid, N-acetyl-beta-neuraminic acid | | 著者 | Strotmeier, J, Gu, S, Jutzi, S, Mahrhold, S, Zhou, J, Pich, A, Bigalke, H, Rummel, A, Jin, R, Binz, T. | | 登録日 | 2011-03-17 | | 公開日 | 2011-06-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Mol.Microbiol., 81, 2011
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1T3C
 | | Clostridium botulinum type E catalytic domain E212Q mutant | | 分子名称: | CHLORIDE ION, ZINC ION, neurotoxin type E | | 著者 | Agarwal, R, Eswaramoorthy, S, Kumaran, D, Binz, T, Swaminathan, S. | | 登録日 | 2004-04-26 | | 公開日 | 2004-06-29 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural analysis of botulinum neurotoxin type E catalytic domain and its mutant Glu212-->Gln reveals the pivotal role of the Glu212 carboxylate in the catalytic pathway
Biochemistry, 43, 2004
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1T3A
 | | Crystal structure of Clostridium botulinum neurotoxin type E catalytic domain | | 分子名称: | CHLORIDE ION, ZINC ION, neurotoxin type E | | 著者 | Agarwal, R, Eswaramoorthy, S, Kumaran, D, Binz, T, Swaminathan, S. | | 登録日 | 2004-04-26 | | 公開日 | 2004-06-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Structural analysis of botulinum neurotoxin type E catalytic domain and its mutant Glu212-->Gln reveals the pivotal role of the Glu212 carboxylate in the catalytic pathway
Biochemistry, 43, 2004
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2NM1
 | | Structure of BoNT/B in complex with its protein receptor | | 分子名称: | Botulinum neurotoxin type B, Synaptotagmin-2 | | 著者 | Jin, R, Rummel, A, Binz, T, Brunger, A.T. | | 登録日 | 2006-10-20 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.
Nature, 444, 2006
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2QN0
 | | Structure of Botulinum neurotoxin serotype C1 light chain protease | | 分子名称: | Neurotoxin, ZINC ION | | 著者 | Jin, R, Sikorra, S, Stegmann, C.M, Pich, A, Binz, T, Brunger, A.T. | | 登録日 | 2007-07-17 | | 公開日 | 2007-09-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural and biochemical studies of botulinum neurotoxin serotype C1 light chain protease: implications for dual substrate specificity.
Biochemistry, 46, 2007
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1ZKX
 | | Crystal structure of Glu158Ala/Thr159Ala/Asn160Ala- a triple mutant of Clostridium botulinum neurotoxin E catalytic domain | | 分子名称: | CHLORIDE ION, ZINC ION, botulinum neurotoxin type E | | 著者 | Agarwal, R, Binz, T, Swaminathan, S. | | 登録日 | 2005-05-04 | | 公開日 | 2005-07-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme.
Biochemistry, 44, 2005
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1ZL6
 | | Crystal structure of Tyr350Ala mutant of Clostridium botulinum neurotoxin E catalytic domain | | 分子名称: | SULFATE ION, ZINC ION, botulinum neurotoxin type E | | 著者 | Agarwal, R, Binz, T, Swaminathan, S. | | 登録日 | 2005-05-05 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme.
Biochemistry, 44, 2005
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1ZN3
 | | Crystal structure of Glu335Ala mutant of Clostridium botulinum neurotoxin type E | | 分子名称: | CHLORIDE ION, ZINC ION, botulinum neurotoxin type E | | 著者 | Agarwal, R, Binz, T, Swaminathan, S. | | 登録日 | 2005-05-11 | | 公開日 | 2005-07-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme.
Biochemistry, 44, 2005
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1YVG
 | | Structural analysis of the catalytic domain of tetanus neurotoxin | | 分子名称: | Tetanus toxin, light chain, ZINC ION | | 著者 | Rao, K.N, Kumaran, D, Binz, T, Swaminathan, S. | | 登録日 | 2005-02-15 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural analysis of the catalytic domain of tetanus neurotoxin.
Toxicon, 45, 2005
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1ZKW
 | | Crystal structure of Arg347Ala mutant of botulinum neurotoxin E catalytic domain | | 分子名称: | CHLORIDE ION, ZINC ION, botulinum neurotoxin type E | | 著者 | Agarwal, R, Binz, T, Swaminathan, S. | | 登録日 | 2005-05-04 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme.
Biochemistry, 44, 2005
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1ZL5
 | | Crystal structure of Glu335Gln mutant of Clostridium botulinum neurotoxin E catalytic domain | | 分子名称: | CHLORIDE ION, botulinum neurotoxin type E | | 著者 | Agarwal, R, Binz, T, Swaminathan, S. | | 登録日 | 2005-05-05 | | 公開日 | 2005-07-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme.
Biochemistry, 44, 2005
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2A8A
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2A97
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6BVD
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3OBT
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3OBR
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5NCH
 | | GriE apo form | | 分子名称: | Leucine hydroxylase | | 著者 | Lukat, P, Blankenfeldt, W, Mueller, R. | | 登録日 | 2017-03-05 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.819 Å) | | 主引用文献 | Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity.
Chem Sci, 8, 2017
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5NCJ
 | | GriE in complex with manganese, succinate and (2S,4R)-5-hydroxyleucine | | 分子名称: | (2S,4R)-5-hydroxyleucine, Leucine hydroxylase, MANGANESE (II) ION, ... | | 著者 | Lukat, P, Blankenfeldt, W, Mueller, R. | | 登録日 | 2017-03-05 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.529 Å) | | 主引用文献 | Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity.
Chem Sci, 8, 2017
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5NCI
 | | GriE in complex with cobalt, alpha-ketoglutarate and l-leucine | | 分子名称: | 2-OXOGLUTARIC ACID, COBALT (II) ION, LEUCINE, ... | | 著者 | Lukat, P, Blankenfeldt, W, Mueller, R. | | 登録日 | 2017-03-05 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.755 Å) | | 主引用文献 | Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity.
Chem Sci, 8, 2017
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