5NCJ
GriE in complex with manganese, succinate and (2S,4R)-5-hydroxyleucine
Summary for 5NCJ
Entry DOI | 10.2210/pdb5ncj/pdb |
Descriptor | Leucine hydroxylase, MANGANESE (II) ION, SUCCINIC ACID, ... (5 entities in total) |
Functional Keywords | fe(ii)/alpha-ketoglutarate dependent dioxygenase, hydroxylase, non-heme iron protein, leucine hydroxylase, 5-hydroxyleucine, (2s4r)-5-hydroxyleucine, 4-methyl-proline, griselimycin, methyl-griselimycin, oxidoreductase |
Biological source | Streptomyces sp. DSM 40835 |
Total number of polymer chains | 2 |
Total formula weight | 60369.38 |
Authors | Lukat, P.,Blankenfeldt, W.,Mueller, R. (deposition date: 2017-03-05, release date: 2017-10-04, Last modification date: 2024-01-17) |
Primary citation | Lukat, P.,Katsuyama, Y.,Wenzel, S.,Binz, T.,Konig, C.,Blankenfeldt, W.,Bronstrup, M.,Muller, R. Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity. Chem Sci, 8:7521-7527, 2017 Cited by PubMed: 29163906DOI: 10.1039/c7sc02622f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.529 Å) |
Structure validation
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