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Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment in complex with an inhibitor 3-Aminobenzoic acid
分子名称:	3-AMINOBENZOIC ACID, CITRIC ACID, Poly [ADP-ribose] polymerase 12
著者	Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hogbom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日	2007-05-02
公開日	2007-05-15
最終更新日	2015-04-22
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein. J.Biol.Chem., 290, 2015

2OXC

Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP
分子名称:	ADENOSINE-5'-DIPHOSPHATE, Probable ATP-dependent RNA helicase DDX20
著者	Karlberg, T, Ogg, D, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日	2007-02-20
公開日	2007-02-27
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.3 Å)
主引用文献	Human DEAD-box RNA helicase DDX20 To be Published

3IQ2

Human sorting nexin 7, phox homology (PX) domain
分子名称:	GLYCEROL, SULFATE ION, Sorting nexin-7
著者	Karlberg, T, Wisniewska, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Schutz, P, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日	2009-08-19
公開日	2009-09-08
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Human Sorting Nexin 7, Phox Homology (Px) Domain To be Published

3HKV

Human poly(ADP-ribose) polymerase 10, catalytic fragment in complex with an inhibitor 3-aminobenzamide
分子名称:	3-aminobenzamide, PHOSPHATE ION, Poly [ADP-ribose] polymerase 10, ...
著者	Karlberg, T, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Kotzsch, A, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Sagemark, J, Schutz, P, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日	2009-05-26
公開日	2009-06-16
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Human Poly(Adp-Ribose) Polymerase 10, Catalytic Fragment in Complex with an Inhibitor 3-Aminobenzamide To be Published

2NZ2

Crystal structure of human argininosuccinate synthase in complex with aspartate and citrulline
分子名称:	ASPARTIC ACID, Argininosuccinate synthase, CITRULLINE, ...
著者	Karlberg, T, Uppenberg, J, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Magnusdottir, A, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日	2006-11-22
公開日	2006-12-05
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Structure of human argininosuccinate synthetase. Acta Crystallogr.,Sect.D, 64, 2008

3B6E

Crystal structure of human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain
分子名称:	Interferon-induced helicase C domain-containing protein 1, SODIUM ION
著者	Karlberg, T, Welin, M, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kallas, A, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日	2007-10-29
公開日	2007-11-13
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain. To be Published

3D8B

Crystal structure of human fidgetin-like protein 1 in complex with ADP
分子名称:	ADENOSINE-5'-DIPHOSPHATE, Fidgetin-like protein 1
著者	Karlberg, T, Wisniewska, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Olesen, K, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Welin, M, Wikstrom, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日	2008-05-23
公開日	2008-08-26
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Human fidgetin-like protein 1. To be Published

3DYD

Human Tyrosine Aminotransferase
分子名称:	PYRIDOXAL-5'-PHOSPHATE, Tyrosine aminotransferase
著者	Karlberg, T, Moche, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Lehtio, L, Nilsson, M.E, Nordlund, P, Nyman, T, Olesen, K, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日	2008-07-27
公開日	2008-08-19
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Human Tyrosine Aminotransferase To be Published

3ELB

Human CTP: Phosphoethanolamine Cytidylyltransferase in complex with CMP
分子名称:	CYTIDINE-5'-MONOPHOSPHATE, Ethanolamine-phosphate cytidylyltransferase, GLYCEROL
著者	Karlberg, T, Welin, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Wikstrom, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日	2008-09-22
公開日	2008-10-21
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Human CTP:Phosphoethanolamine Cytidylyltransferase To be Published

2QZ4

Human paraplegin, AAA domain in complex with ADP
分子名称:	ADENOSINE-5'-DIPHOSPHATE, Paraplegin
著者	Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, J, Sagemark, C, Sundstrom, M, Thorsell, A.G, Tresauges, L, Van Den Berg, S, Weigelt, J, Welin, M, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
登録日	2007-08-16
公開日	2007-09-11
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.22 Å)
主引用文献	Crystal Structure of the ATPase Domain of the Human AAA+ Protein Paraplegin/SPG7. Plos One, 4, 2009

3GEY

Crystal structure of human poly(ADP-ribose) polymerase 15, catalytic fragment in complex with an inhibitor Pj34
分子名称:	N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE, Poly [ADP-ribose] polymerase 15
著者	Karlberg, T, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日	2009-02-26
公開日	2009-03-24
最終更新日	2024-05-29
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein. J.Biol.Chem., 290, 2015

2X5Y

Human ZC3HAV1 (ARTD13), C-terminal domain
分子名称:	ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1
著者	Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kallas, A, Kotenyova, T, Kraulis, P, Moche, M, Nordlund, P, Nyman, T, Persson, C, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H.
登録日	2010-02-11
公開日	2010-03-02
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (1.05 Å)
主引用文献	Structural Basis for Lack of Adp-Ribosyltransferase Activity in Poly(Adp-Ribose) Polymerase-13/Zinc Finger Antiviral Protein. J.Biol.Chem., 290, 2015

3BLJ

Crystal structure of human poly(ADP-ribose) polymerase 15, catalytic fragment
分子名称:	CHLORIDE ION, GLYCEROL, Poly(ADP-ribose) polymerase 15, ...
著者	Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Welin, M, Weigelt, J, Structural Genomics Consortium (SGC)
登録日	2007-12-11
公開日	2007-12-25
最終更新日	2024-05-29
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein. J.Biol.Chem., 290, 2015

3OLH

Human 3-mercaptopyruvate sulfurtransferase
分子名称:	3-mercaptopyruvate sulfurtransferase, SODIUM ION, SULFATE ION
著者	Karlberg, T, Collins, R, Arrowsmith, C.H, Berglund, H, Bountra, C, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kotenyova, T, Kouznetsova, E, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schutz, P, Sehic, A, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日	2010-08-26
公開日	2010-09-29
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Human 3-Mercaptopyruvate Sulfurtransferase To be Published

3KJD

Human poly(ADP-ribose) polymerase 2, catalytic fragment in complex with an inhibitor ABT-888
分子名称:	(2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, GLYCEROL, Poly [ADP-ribose] polymerase 2
著者	Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日	2009-11-03
公開日	2009-11-17
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888. Biochemistry, 49, 2010

3KR7

Human tankyrase 2 - catalytic PARP domain
分子名称:	GLYCEROL, SULFATE ION, Tankyrase-2, ...
著者	Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日	2009-11-18
公開日	2009-12-15
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor. J.Med.Chem., 53, 2010

3KR8

Human tankyrase 2 - catalytic PARP domain in complex with an inhibitor XAV939
分子名称:	2-[4-(trifluoromethyl)phenyl]-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-4-ol, GLYCEROL, SULFATE ION, ...
著者	Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日	2009-11-18
公開日	2009-12-15
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor. J.Med.Chem., 53, 2010

3KCZ

Human poly(ADP-ribose) polymerase 2, catalytic fragment in complex with an inhibitor 3-aminobenzamide
分子名称:	3-aminobenzamide, GLYCEROL, Poly [ADP-ribose] polymerase 2
著者	Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日	2009-10-22
公開日	2009-11-10
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888. Biochemistry, 49, 2010

2Q2O

Crystal structure of H183C Bacillus subtilis ferrochelatase in complex with deuteroporphyrin IX 2,4-disulfonic acid dihydrochloride
分子名称:	Ferrochelatase, MAGNESIUM ION, PROTOPORPHYRIN IX 2,4-DISULFONIC ACID
著者	Karlberg, T, Thorvaldsen, O.H, Al-Karadaghi, S.
登録日	2007-05-29
公開日	2008-06-17
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Porphyrin binding and distortion and substrate specificity in the ferrochelatase reaction: the role of active site residues J.Mol.Biol., 378, 2008

2Q3J

Crystal structure of the His183Ala variant of Bacillus subtilis ferrochelatase in complex with N-Methyl Mesoporphyrin
分子名称:	Ferrochelatase, MAGNESIUM ION, N-METHYL PROTOPORPHYRIN IX 2,4-DISULFONIC ACID
著者	Karlberg, T, Thorvaldsen, O.H, Al-Karadaghi, S.
登録日	2007-05-30
公開日	2008-04-22
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.39 Å)
主引用文献	Porphyrin binding and distortion and substrate specificity in the ferrochelatase reaction: the role of active site residues J.Mol.Biol., 378, 2008

1WM0

PPARgamma in complex with a 2-BABA compound
分子名称:	14-mer from Nuclear receptor coactivator 2, 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID, Peroxisome proliferator activated receptor gamma
著者	Ostberg, T, Svensson, S, Selen, G, Uppenberg, J, Thor, M, Sundbom, M, Sydow-Backman, M, Gustavsson, A.L, Jendeberg, L.
登録日	2004-07-01
公開日	2004-09-07
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	A new class of peroxisome proliferator-activated receptor agonists with a novel binding epitope shows antidiabetic effects J.Biol.Chem., 279, 2004

4X52

Human PARP13 (ZC3HAV1), C-Terminal PARP Domain (H810N; N830Y variant)
分子名称:	GLYCEROL, SULFATE ION, Zinc finger CCCH-type antiviral protein 1
著者	Karlberg, T, Thorsell, A.G, Klepsch, M, Schuler, H.
登録日	2014-12-04
公開日	2015-02-11
最終更新日	2024-01-10
実験手法	X-RAY DIFFRACTION (2.08 Å)
主引用文献	Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein. J.Biol.Chem., 290, 2015

3GOQ

Crystal structure of the Tyr13Met variant of Bacillus subtilis ferrochelatase
分子名称:	Ferrochelatase, MAGNESIUM ION
著者	Karlberg, T, Hansson, M.D, Hansson, M, Al-Karadaghi, S.
登録日	2009-03-19
公開日	2010-03-31
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Crystal structure of the Tyr13Met variant of Bacillus subtilis ferrochelatase To be Published

6HXS

Human PARP16 (ARTD15) IN COMPLEX WITH CARBA-NAD
分子名称:	ADENOSINE, CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, ...
著者	Karlberg, T, Pinto, A.F, Thorsell, A.G, Schuler, H.
登録日	2018-10-18
公開日	2019-10-30
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	Human PARP16 (ARTD15) IN COMPLEX WITH CARBA-NAD To Be Published

6HXR

Human PARP16 (ARTD15) IN COMPLEX WITH EB-47
分子名称:	2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, Mono [ADP-ribose] polymerase PARP16
著者	Karlberg, T, Pinto, A.F, Thorsell, A.G, Schuler, H.
登録日	2018-10-18
公開日	2019-10-30
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Human PARP16 (ARTD15) IN COMPLEX WITH EB-47 To Be Published

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全ヒット件数:	658
表示件数:	25
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