3HKV

Human poly(ADP-ribose) polymerase 10, catalytic fragment in complex with an inhibitor 3-aminobenzamide

Summary for 3HKV

• Entry DOI: 10.2210/pdb3hkv/pdb
• Descriptor: Poly [ADP-ribose] polymerase 10, PHOSPHATE ION, SODIUM ION, ... (5 entities in total)
• Functional Keywords: parp, poly(adp-ribose) polymerase, nad, transferase, structural genomics, structural genomics consortium, sgc, cytoplasm, glycosyltransferase, nucleus, phosphoprotein, polymorphism
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus, nucleolus : Q53GL7
• Total number of polymer chains: 2
• Total formula weight: 49564.61

Authors

Karlberg, T.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kotenyova, T.,Kotzsch, A.,Nielsen, T.K.,Nordlund, P.,Nyman, T.,Persson, C.,Roos, A.K.,Sagemark, J.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wisniewska, M.,Schuler, H.,Structural Genomics Consortium (SGC) (deposition date: 2009-05-26, release date: 2009-06-16, Last modification date: 2023-11-01)

• Primary citation: Karlberg, T.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kotenyova, T.,Kotzsch, A.,Nielsen, T.K.,Nordlund, P.,Nyman, T.,Persson, C.,Roos, A.K.,Sagemark, J.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wisniewska, M.,Schuler, H.; Human Poly(Adp-Ribose) Polymerase 10, Catalytic Fragment in Complex with an Inhibitor 3-Aminobenzamide; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)