3HKV
Human poly(ADP-ribose) polymerase 10, catalytic fragment in complex with an inhibitor 3-aminobenzamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Poly [ADP-ribose] polymerase 10 | polymer | 217 | 24480.7 | 2 | UniProt (Q53GL7) Pfam (PF00644) In PDB | Homo sapiens (human) | PARP-10 |
2 | A | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
3 | A, B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
4 | A, B | 3-aminobenzamide | non-polymer | 136.2 | 2 | Chemie (3AB) | |||
5 | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A, B: 809 - 1017 (UniProt: Q53GL7)
PDB | External Database | Details |
---|---|---|
Met 808 | - | expression tag |
Lys 922 | Arg 922 | engineered mutation |
Met 979 | Val 979 | engineered mutation |
Ala 1018 | - | expression tag |
His 1019 | - | expression tag |
His 1020 | - | expression tag |
His 1021 | - | expression tag |
His 1022 | - | expression tag |
His 1023 | - | expression tag |
His 1024 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 48961.4 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 603.2 | |
All* | Total formula weight | 49564.6 |