2X5Y
Human ZC3HAV1 (ARTD13), C-terminal domain
Summary for 2X5Y
Entry DOI | 10.2210/pdb2x5y/pdb |
Descriptor | ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1 (2 entities in total) |
Functional Keywords | antiviral defense, immune system, transferase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Isoform 1: Cytoplasm. Isoform 2: Cytoplasm: Q7Z2W4 |
Total number of polymer chains | 1 |
Total formula weight | 20309.09 |
Authors | Karlberg, T.,Schutz, P.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Kallas, A.,Kotenyova, T.,Kraulis, P.,Moche, M.,Nordlund, P.,Nyman, T.,Persson, C.,Siponen, M.I.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wisniewska, M.,Schuler, H. (deposition date: 2010-02-11, release date: 2010-03-02, Last modification date: 2023-12-20) |
Primary citation | Karlberg, T.,Klepsch, M.,Thorsell, A.,Andersson, C.D.,Linusson, A.,Schuler, H. Structural Basis for Lack of Adp-Ribosyltransferase Activity in Poly(Adp-Ribose) Polymerase-13/Zinc Finger Antiviral Protein. J.Biol.Chem., 290:7336-, 2015 Cited by PubMed: 25635049DOI: 10.1074/JBC.M114.630160 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.05 Å) |
Structure validation
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