3KR7
Human tankyrase 2 - catalytic PARP domain
Summary for 3KR7
Entry DOI | 10.2210/pdb3kr7/pdb |
Related | 3KR8 |
Descriptor | Tankyrase-2, ZINC ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | catalytic fragment, parp, structural genomics, structural genomics consortium, sgc, adp-ribosylation, ank repeat, chromosomal protein, glycosyltransferase, golgi apparatus, membrane, mrna transport, nad, nuclear pore complex, nucleus, phosphorylation, protein transport, telomere, transferase, translocation, transport, wnt-signalling |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9H2K2 |
Total number of polymer chains | 1 |
Total formula weight | 27741.49 |
Authors | Karlberg, T.,Schutz, P.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kallas, A.,Kotenyova, T.,Kotzsch, A.,Kraulis, P.,Nielsen, T.K.,Moche, M.,Nordlund, P.,Nyman, T.,Persson, C.,Siponen, M.I.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wisniewska, M.,Schuler, H.,Structural Genomics Consortium (SGC) (deposition date: 2009-11-18, release date: 2009-12-15, Last modification date: 2023-11-01) |
Primary citation | Karlberg, T.,Markova, N.,Johansson, I.,Hammarstrom, M.,Schutz, P.,Weigelt, J.,Schuler, H. Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor. J.Med.Chem., 53:5352-5355, 2010 Cited by PubMed: 20565110DOI: 10.1021/jm100249w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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