7MXE
| Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 Fab heavy chain, ... | 著者 | Abernathy, M.E, Bjorkman, P.J. | 登録日 | 2021-05-19 | 公開日 | 2021-10-27 | 最終更新日 | 2021-11-03 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope. Npj Vaccines, 6, 2021
|
|
7K8X
| Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ... | 著者 | Abernathy, M.E, Barnes, C.O, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|
8D47
| |
8D48
| sd1.040 Fab in complex with SARS-CoV-2 Spike 2P glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, sd1.040 Fab heavy chain, ... | 著者 | Abernathy, M.E, Barnes, C.O. | 登録日 | 2022-06-01 | 公開日 | 2023-01-25 | 最終更新日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein. Sci Immunol, 8, 2023
|
|
6ORO
| Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab874NHP antibody Fab heavy chain, ... | 著者 | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | 登録日 | 2019-04-30 | 公開日 | 2019-06-12 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
|
|
6ORN
| Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074 | 分子名称: | 10-1074 antibody Fab heavy chain, 10-1074 antibody Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | 登録日 | 2019-04-30 | 公開日 | 2019-06-12 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
|
|
6ORQ
| Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab275MUR antibody Fab heavy chain, ... | 著者 | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | 登録日 | 2019-04-30 | 公開日 | 2019-06-12 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
|
|
6ORP
| Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab897NHP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab897NHP antibody Fab heavy chain, ... | 著者 | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | 登録日 | 2019-04-30 | 公開日 | 2019-06-12 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
|
|
6UDK
| HIV-1 bNAb 1-55 in complex with modified BG505 SOSIP-based immunogen RC1 and 10-1074 | 分子名称: | 1-55 Fab Heavy Chain, 1-55 Fab Light Chain, 10-1074 Fab Heavy Chain, ... | 著者 | Abernathy, M.E, Barnes, C.O, Gristick, H.B, Bjorkman, P.J. | 登録日 | 2019-09-19 | 公開日 | 2020-01-29 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell, 180, 2020
|
|
6UDJ
| HIV-1 bNAb 1-18 in complex with BG505 SOSIP.664 and 10-1074 | 分子名称: | 1-18 Fab Heavy Chain, 1-18 Fab Light Chain, 10-1074 Fab Heavy Chain, ... | 著者 | Abernathy, M.E, Barnes, C.O, Gristick, H.B, Bjorkman, P.J. | 登録日 | 2019-09-19 | 公開日 | 2020-01-29 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell, 180, 2020
|
|
7K8Q
| Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C121 | 分子名称: | C121 Fab Heavy Chain, C121 Fab Light Chain, GLYCEROL | 著者 | Abernathy, M.E, Barnes, C.O, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|
7K8Y
| Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ... | 著者 | Abernathy, M.E, Barnes, C.O, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|
7K8N
| Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C102 | 分子名称: | C102 Fab Heavy Chain, C102 Fab Light Chain, DI(HYDROXYETHYL)ETHER, ... | 著者 | Jette, C.A, Barnes, C.O, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|
8E7M
| |
7TQG
| |
7K8U
| Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C104 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C104 Fab Heavy Chain, ... | 著者 | Barnes, C.O, Malyutin, A.G, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|
7K90
| Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C144 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C144 Fab Heavy Chain, C144 Fab Light Chain, ... | 著者 | Barnes, C.O, Esswein, S.R, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|
7K8T
| Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C002 (State 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ... | 著者 | Malyutin, A.G, Barnes, C.O, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|
7K8S
| Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C002 (state 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ... | 著者 | Barnes, C.O, Malyutin, A.G, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|
7K8M
| Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C102 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C102 Fab Heavy Chain, C102 Fab Light Chain, ... | 著者 | Jette, C.A, Barnes, C.O, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|
7K8V
| Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C110 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C110 Fab Heavy Chain, ... | 著者 | Dam, K.A, Barnes, C.O, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|
7K8O
| Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C002 | 分子名称: | C002 Fab Heavy Chain, C002 Fab Light Chain, GLYCEROL, ... | 著者 | Jette, C.A, Barnes, C.O, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|
7K8W
| Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C119 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C119 Fab Heavy Chain, ... | 著者 | Sharaf, N.G, Barnes, C.O, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|
7K8P
| |
7K8R
| Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C135 | 分子名称: | C135 Fab Heavy Chain, C135 Fab Light Chain, GLYCEROL | 著者 | Jette, C.A, Barnes, C.O, Bjorkman, P.J. | 登録日 | 2020-09-27 | 公開日 | 2020-10-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
|
|