8E7M

Structure of the human ACE2 receptor in complex with antibody Fab fragment, 05B04

Summary for 8E7M

• Entry DOI: 10.2210/pdb8e7m/pdb
• EMDB information: 27939
• Descriptor: Angiotensin-converting enzyme 2, 05B04 Heavy Chain, 05B04 Light Chain, ... (6 entities in total)
• Functional Keywords: ace2, antibody, sars-cov-2, inhibition, antiviral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 122033.32

Authors

Barnes, C.O. (deposition date: 2022-08-24, release date: 2022-09-28)

• Primary citation: Zhang, F.,Jenkins, J.,de Carvalho, R.V.,Nakandakari-Higa, S.,Chen, T.,Abernathy, M.E.,Nyakatura, E.,Andrew, D.,Lebedeva, I.,Lorenz, I.C.,Hoffmann, H.H.,Rice, C.M.,Victora, G.D.,Barnes, C.O.,Haziioannou, T.,Bieniasz, P.D.; Human anti-ACE2 monoclonal antibodies as pan-sarbecovirus prophylactic agents; Biorxiv, 2022; DOI: 10.1101/2022.08.24.505169

Experimental method

ELECTRON MICROSCOPY (3.3 Å)