8E7M

Structure of the human ACE2 receptor in complex with antibody Fab fragment, 05B04

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Angiotensin-converting enzyme 2	polymer	626	72306.2	1	UniProt (Q9BYF1) Pfam (PF01401) In PDB	Homo sapiens (human)	Angiotensin-converting enzyme homolog,ACEH,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15,hACE2
2	H	05B04 Heavy Chain	polymer	227	23948.8	1		Homo sapiens (human)
3	L	05B04 Light Chain	polymer	214	23549.2	1		Homo sapiens (human)
4	B, C	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	2	In PDB GlyTouCan (G21290RB)
5	D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A: 1 - 615 (UniProt: Q9BYF1)

PDB	External Database	Details
Gly 616	-	expression tag
Ser 617	-	expression tag
Gly 618	-	expression tag
His 619	-	expression tag
His 620	-	expression tag
His 621	-	expression tag
His 622	-	expression tag
His 623	-	expression tag
His 624	-	expression tag
His 625	-	expression tag
His 626	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	119804.2
Branched	Number of molecules	3
	Total formula weight	1565.5
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	122033.3

*Water molecules are not included.