8D48

sd1.040 Fab in complex with SARS-CoV-2 Spike 2P glycoprotein

Summary for 8D48

Entry DOI	10.2210/pdb8d48/pdb
EMDB information	27177
Descriptor	Spike glycoprotein, sd1.040 Fab heavy chain, sd1.040 Fab light chain, ... (4 entities in total)
Functional Keywords	antibody, sd1, sars-cov-2, complex, antiviral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	3
Total formula weight	189505.12
Authors	Abernathy, M.E.,Barnes, C.O. (deposition date: 2022-06-01, release date: 2023-01-25, Last modification date: 2023-03-22)
Primary citation	Bianchini, F.,Crivelli, V.,Abernathy, M.E.,Guerra, C.,Palus, M.,Muri, J.,Marcotte, H.,Piralla, A.,Pedotti, M.,De Gasparo, R.,Simonelli, L.,Matkovic, M.,Toscano, C.,Biggiogero, M.,Calvaruso, V.,Svoboda, P.,Cervantes Rincon, T.,Fava, T.,Podesvova, L.,Shanbhag, A.A.,Celoria, A.,Sgrignani, J.,Stefanik, M.,Honig, V.,Pranclova, V.,Michalcikova, T.,Prochazka, J.,Guerrini, G.,Mehn, D.,Ciabattini, A.,Abolhassani, H.,Jarrossay, D.,Uguccioni, M.,Medaglini, D.,Pan-Hammarstrom, Q.,Calzolai, L.,Fernandez, D.,Baldanti, F.,Franzetti-Pellanda, A.,Garzoni, C.,Sedlacek, R.,Ruzek, D.,Varani, L.,Cavalli, A.,Barnes, C.O.,Robbiani, D.F. Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein. Sci Immunol, 8:eade0958-eade0958, 2023 Cited by PubMed: 36701425 DOI: 10.1126/sciimmunol.ade0958 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation