5CCA
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![BU of 5cca by Molmil](/molmil-images/mine/5cca) | Crystal structure of Mtb toxin | 分子名称: | Endoribonuclease MazF3 | 著者 | Cascio, D, Arbing, M, de Serrano, V, Eisenberg, D, Miallau, L, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2015-07-01 | 公開日 | 2016-09-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of Mtb toxin To Be Published
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4Q0G
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1GR0
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![BU of 1gr0 by Molmil](/molmil-images/mine/1gr0) | myo-inositol 1-phosphate synthase from Mycobacterium tuberculosis in complex with NAD and zinc. | 分子名称: | CACODYLATE ION, INOSITOL-3-PHOSPHATE SYNTHASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Norman, R.A, Murray-Rust, J, McDonald, N.Q, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2001-12-10 | 公開日 | 2002-03-12 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure of Inositol 1-Phosphate Synthase from Mycobacterium Tuberculosis, a Key Enzyme in Phosphatidylinositol Synthesis Structure, 10, 2002
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1QPQ
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![BU of 1qpq by Molmil](/molmil-images/mine/1qpq) | Structure of Quinolinic Acid Phosphoribosyltransferase from Mycobacterium Tuberculosis: A Potential TB Drug Target | 分子名称: | QUINOLINATE PHOSPHORIBOSYLTRANSFERASE, QUINOLINIC ACID, SULFATE ION | 著者 | Sharma, V, Grubmeyer, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 1998-11-20 | 公開日 | 1998-11-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target. Structure, 6, 1998
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1QPR
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![BU of 1qpr by Molmil](/molmil-images/mine/1qpr) | QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (QAPRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHTHALATE AND PRPCP | 分子名称: | 1-O-[(R)-hydroxy(phosphonomethyl)phosphoryl]-5-O-phosphono-alpha-D-ribofuranose, MANGANESE (II) ION, PHTHALIC ACID, ... | 著者 | Sharma, V, Grubmeyer, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 1998-10-17 | 公開日 | 1998-10-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target. Structure, 6, 1998
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1QPN
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1C3V
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![BU of 1c3v by Molmil](/molmil-images/mine/1c3v) | DIHYDRODIPICOLINATE REDUCTASE FROM MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND PDC | 分子名称: | DIHYDRODIPICOLINATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PYRIDINE-2,6-DICARBOXYLIC ACID, ... | 著者 | Cirilli, M, Zheng, R, Scapin, G, Blanchard, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 1999-07-28 | 公開日 | 2003-08-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | The three-dimensional structures of the Mycobacterium tuberculosis
dihydrodipicolinate reductase-NADH-2,6-PDC and -NADPH-2,6-PDC complexes.
Structural and mutagenic analysis of relaxed nucleotide specificity Biochemistry, 42, 2003
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7SFR
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![BU of 7sfr by Molmil](/molmil-images/mine/7sfr) | Unmethylated Mtb Ribosome 50S with SEQ-9 | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Xing, Z, Cui, Z, Zhang, J, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2021-10-04 | 公開日 | 2022-10-12 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents. Cell, 186, 2023
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1Q7T
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![BU of 1q7t by Molmil](/molmil-images/mine/1q7t) | Rv1170 (MshB) from Mycobacterium tuberculosis | 分子名称: | SULFATE ION, hypothetical protein Rv1170, octyl beta-D-glucopyranoside | 著者 | McCarthy, A.A, Peterson, N.A, Knijff, R, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-08-20 | 公開日 | 2004-01-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of MshB from Mycobacterium tuberculosis, a Deacetylase Involved in Mycothiol Biosynthesis. J.Mol.Biol., 335, 2004
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1Q74
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![BU of 1q74 by Molmil](/molmil-images/mine/1q74) | The Crystal Structure of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB) | 分子名称: | 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB), 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ZINC ION | 著者 | Maynes, J.T, Garen, C, Cherney, M.M, Newton, G, Arad, D, Av-Gay, Y, Fahey, R.C, James, M.N, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2003-08-15 | 公開日 | 2003-12-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Crystal Structure of 1-D-myo-Inositol 2-Acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB) from Mycobacterium tuberculosis Reveals a Zinc Hydrolase with a Lactate Dehydrogenase Fold. J.Biol.Chem., 278, 2003
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6PK2
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![BU of 6pk2 by Molmil](/molmil-images/mine/6pk2) | CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS | 分子名称: | 2-{4-[(6-fluoro-1,3-benzothiazol-2-yl)oxy]-2-hydroxyphenyl}-N-methylacetamide, Propionyl-CoA carboxylase subunit beta | 著者 | Reddy, M.C.M, Nian, Z, Michele, T.C.B, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2019-06-28 | 公開日 | 2020-07-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Elucidating the Inhibition and specificity of binding of
herbicidal aryloxyphenoxypropionates derivatives to Mycobacterium tuberculosis carboxyltransferase
domain of acetyl-coenzyme A(AccD6). To Be Published
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6P02
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![BU of 6p02 by Molmil](/molmil-images/mine/6p02) | Crystal structure of Mtb aspartate decarboxylase, 6-Chlorine pyrazinoic acid complex | 分子名称: | 6-chloropyrazine-2-carboxylic acid, Aspartate 1-decarboxylase alpha chain, Aspartate 1-decarboxylase beta chain | 著者 | Sun, Q, Li, X, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2019-05-16 | 公開日 | 2020-02-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD. Nat Commun, 11, 2020
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6OZ8
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6P1Y
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![BU of 6p1y by Molmil](/molmil-images/mine/6p1y) | Crystal structure of Mtb aspartate decarboxylase mutant M117I | 分子名称: | AMMONIUM ION, Aspartate 1-decarboxylase alpha chain, Aspartate 1-decarboxylase beta chain, ... | 著者 | Sun, Q, Li, X, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2019-05-20 | 公開日 | 2020-02-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD. Nat Commun, 11, 2020
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3C90
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![BU of 3c90 by Molmil](/molmil-images/mine/3c90) | The 1.25 A Resolution Structure of Phosphoribosyl-ATP Pyrophosphohydrolase from Mycobacterium tuberculosis, crystal form II | 分子名称: | Phosphoribosyl-ATP pyrophosphatase | 著者 | Javid-Majd, F, Yang, D, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2008-02-14 | 公開日 | 2008-04-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 64, 2008
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3BUE
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![BU of 3bue by Molmil](/molmil-images/mine/3bue) | Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis | 分子名称: | Arginine repressor ArgR | 著者 | Cherney, L.T, Cherney, M.M, Garen, C.R, Lu, G.J, James, M.N.G, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2008-01-02 | 公開日 | 2008-01-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 64, 2008
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2A6P
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![BU of 2a6p by Molmil](/molmil-images/mine/2a6p) | Structure Solution to 2.2 Angstrom and Functional Characterisation of the Open Reading Frame Rv3214 from Mycobacterium tuberculosis | 分子名称: | GLYCEROL, POSSIBLE PHOSPHOGLYCERATE MUTASE GPM2, SULFATE ION | 著者 | Watkins, H.A, Yu, M, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2005-07-03 | 公開日 | 2006-05-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and Functional Analysis of Rv3214 from Mycobacterium tuberculosis, a Protein with Conflicting Functional Annotations, Leads to Its Characterization as a Phosphatase. J.Bacteriol., 188, 2006
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5BO3
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1ZVW
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![BU of 1zvw by Molmil](/molmil-images/mine/1zvw) | The Crystal Structure of TrpD (Rv2192c) from Mycobacterium tuberculosis in Complex with PRPP and Magnesium | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, BENZAMIDINE, ... | 著者 | Lee, C.E, Lott, J.S, Baker, E.N, Arcus, V.L, Javid-Majd, F, Goodfellow, C, Hung, L.-W, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2005-06-02 | 公開日 | 2006-01-17 | 最終更新日 | 2021-08-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Crystal Structure of TrpD, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate. J.Mol.Biol., 355, 2006
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2A86
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![BU of 2a86 by Molmil](/molmil-images/mine/2a86) | Crystal structure of A Pantothenate synthetase complexed with AMP and beta-alanine | 分子名称: | ADENOSINE MONOPHOSPHATE, BETA-ALANINE, ETHANOL, ... | 著者 | Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2005-07-07 | 公開日 | 2006-02-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of the Pantothenate Synthetase from Mycobacterium tuberculosis, Snapshots of the Enzyme in Action. Biochemistry, 45, 2006
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2A84
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![BU of 2a84 by Molmil](/molmil-images/mine/2a84) | Crystal structure of A Pantothenate synthetase complexed with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2005-07-07 | 公開日 | 2006-02-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal Structure of the Pantothenate Synthetase from Mycobacterium tuberculosis, Snapshots of the Enzyme in Action. Biochemistry, 45, 2006
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2A88
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![BU of 2a88 by Molmil](/molmil-images/mine/2a88) | Crystal structure of A Pantothenate synthetase, apo enzyme in C2 space group | 分子名称: | GLYCEROL, Pantoate--beta-alanine ligase, SULFATE ION | 著者 | Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2005-07-07 | 公開日 | 2006-02-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of the Pantothenate Synthetase from Mycobacterium tuberculosis, Snapshots of the Enzyme in Action. Biochemistry, 45, 2006
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2A7X
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![BU of 2a7x by Molmil](/molmil-images/mine/2a7x) | Crystal Structure of A Pantothenate synthetase complexed with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, GLYCEROL, Pantoate-beta-alanine ligase, ... | 著者 | Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2005-07-06 | 公開日 | 2006-02-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of the Pantothenate Synthetase from Mycobacterium tuberculosis, Snapshots of the Enzyme in Action. Biochemistry, 45, 2006
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5BO2
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![BU of 5bo2 by Molmil](/molmil-images/mine/5bo2) | |
5BNE
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![BU of 5bne by Molmil](/molmil-images/mine/5bne) | |