7SFR

Unmethylated Mtb Ribosome 50S with SEQ-9

This is a non-PDB format compatible entry.

Summary for 7SFR

• Entry DOI: 10.2210/pdb7sfr/pdb
• EMDB information: 22865 25100
• Descriptor: 50S ribosomal protein L32, 50S ribosomal protein L3, 50S ribosomal protein L4, ... (54 entities in total)
• Functional Keywords: unmethylated, mtb ribosome, drug discovery, seq-9, structural genomics, tb structural genomics consortium, tbsgc, ribosome-antibiotic complex, ribosome/antibiotic
• Biological source: Mycobacterium tuberculosis; More
• Total number of polymer chains: 51
• Total formula weight: 2243571.27

Authors

Xing, Z.,Cui, Z.,Zhang, J.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2021-10-04, release date: 2022-10-12, Last modification date: 2023-03-15)

• Primary citation: Zhang, J.,Lair, C.,Roubert, C.,Amaning, K.,Barrio, M.B.,Benedetti, Y.,Cui, Z.,Xing, Z.,Li, X.,Franzblau, S.G.,Baurin, N.,Bordon-Pallier, F.,Cantalloube, C.,Sans, S.,Silve, S.,Blanc, I.,Fraisse, L.,Rak, A.,Jenner, L.B.,Yusupova, G.,Yusupov, M.,Zhang, J.,Kaneko, T.,Yang, T.J.,Fotouhi, N.,Nuermberger, E.,Tyagi, S.,Betoudji, F.,Upton, A.,Sacchettini, J.C.,Lagrange, S.; Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents.; Cell, 186:1013-, 2023; PubMed: 36827973; DOI: 10.1016/j.cell.2023.01.043

Experimental method

ELECTRON MICROSCOPY (2.6 Å)