6PK2

CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS

Summary for 6PK2

• Entry DOI: 10.2210/pdb6pk2/pdb
• Descriptor: Propionyl-CoA carboxylase subunit beta, 2-{4-[(6-fluoro-1,3-benzothiazol-2-yl)oxy]-2-hydroxyphenyl}-N-methylacetamide (3 entities in total)
• Functional Keywords: crotonase super family, carboxyltransferase, transferase-herbicide, structural genomics, transferase, psi-biology, protein structure initiative, tb structural genomics consortium, tbsgc
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 8
• Total formula weight: 404250.26

Authors

Reddy, M.C.M.,Nian, Z.,Michele, T.C.B.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2019-06-28, release date: 2020-07-01, Last modification date: 2024-03-13)

• Primary citation: Reddy, M.C.M.,Nian, Z.,Sacchettini, J.C.; Elucidating the Inhibition and specificity of binding of herbicidal aryloxyphenoxypropionates derivatives to Mycobacterium tuberculosis carboxyltransferase domain of acetyl-coenzyme A(AccD6).; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.402 Å)