1Q74

The Crystal Structure of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB)

Summary for 1Q74

• Entry DOI: 10.2210/pdb1q74/pdb
• Descriptor: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB), ZINC ION, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... (4 entities in total)
• Functional Keywords: rossmann fold, zinc aminohydrolase, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, hydrolase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 4
• Total formula weight: 127724.99

Authors

Maynes, J.T.,Garen, C.,Cherney, M.M.,Newton, G.,Arad, D.,Av-Gay, Y.,Fahey, R.C.,James, M.N.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2003-08-15, release date: 2003-12-02, Last modification date: 2024-02-21)

• Primary citation: Maynes, J.T.,Garen, C.,Cherney, M.M.,Newton, G.,Arad, D.,Av-Gay, Y.,Fahey, R.C.,James, M.N.; The Crystal Structure of 1-D-myo-Inositol 2-Acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB) from Mycobacterium tuberculosis Reveals a Zinc Hydrolase with a Lactate Dehydrogenase Fold.; J.Biol.Chem., 278:47166-47170, 2003; PubMed: 12958317; DOI: 10.1074/jbc.M308914200

Experimental method

X-RAY DIFFRACTION (1.7 Å)