7VS3
 
 | | The crystal structure of rat calcium-dependent activator protein for secretion (CAPS) C2PH | | 分子名称: | Calcium-dependent secretion activator 1, SULFATE ION | | 著者 | Zhou, H, Wei, Z.Q, Zhang, L, Ren, Y.J, Ma, C. | | 登録日 | 2021-10-25 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | | 主引用文献 | The C 2 and PH domains of CAPS constitute an effective PI(4,5)P2-binding unit essential for Ca 2+ -regulated exocytosis.
Structure, 31, 2023
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7VZG
 | | Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c (the larger form) | | 分子名称: | BACTERIOCHLOROPHYLL A, CALCIUM ION, CHLOROPHYLL A, ... | | 著者 | Huang, G.Q, Dong, S.S, Qin, X.C, Sui, S.F. | | 登録日 | 2021-11-16 | | 公開日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | | 主引用文献 | Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c.
Nat Commun, 13, 2022
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6LMR
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5WVH
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5T0M
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7BP3
 | | Cryo-EM structure of the human MCT2 | | 分子名称: | Monocarboxylate transporter 2 | | 著者 | Zhang, B, Jin, Q, Zhang, X, Guo, J, Ye, S. | | 登録日 | 2020-03-21 | | 公開日 | 2020-06-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cooperative transport mechanism of human monocarboxylate transporter 2.
Nat Commun, 11, 2020
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5WUP
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5WVG
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5WUS
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5WVB
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3WMC
 | | Crystal structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with naphthalimide derivative Q2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(dimethylamino)-2-(2-{[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]amino}ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione, Beta-hexosaminidase | | 著者 | Chen, L, Zhou, Y, Chen, L, Yang, Q. | | 登録日 | 2013-11-16 | | 公開日 | 2014-11-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.095 Å) | | 主引用文献 | A crystal structure-guided rational design switching non-carbohydrate inhibitors' specificity between two beta-GlcNAcase homologs
Sci Rep, 4, 2014
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3UBX
 | | Crystal structure of the mouse CD1d-C20:2-aGalCer-L363 mAb Fab complex | | 分子名称: | (11Z,14Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yu, E.D, Zajonc, D.M. | | 登録日 | 2011-10-25 | | 公開日 | 2011-11-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for the recognition of C20:2-alpha GalCer by the invariant natural killer T cell receptor-like antibody L363.
J.Biol.Chem., 287, 2012
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3PKJ
 | | Human SIRT6 crystal structure in complex with 2'-N-Acetyl ADP ribose | | 分子名称: | NAD-dependent deacetylase sirtuin-6, SULFATE ION, UNKNOWN ATOM OR ION, ... | | 著者 | Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Walker, J.R, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC) | | 登録日 | 2010-11-11 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structure and biochemical functions of SIRT6.
J.Biol.Chem., 286, 2011
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3PKI
 | | Human SIRT6 crystal structure in complex with ADP ribose | | 分子名称: | NAD-dependent deacetylase sirtuin-6, SULFATE ION, UNKNOWN ATOM OR ION, ... | | 著者 | Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Bochkarev, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC) | | 登録日 | 2010-11-11 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structure and biochemical functions of SIRT6.
J.Biol.Chem., 286, 2011
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3TVM
 | | Structure of the mouse CD1d-SMC124-iNKT TCR complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Girardi, E, Li, Y, Zajonc, D.M. | | 登録日 | 2011-09-20 | | 公開日 | 2012-02-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Glycolipids that Elicit IFN-gama-Biased Responses from Natural Killer T Cells
Chem.Biol., 18, 2011
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3WMB
 | | Crystal structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with naphthalimide derivative Q1 | | 分子名称: | 2-(2-{[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]amino}ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-hexosaminidase | | 著者 | Liu, T, Zhou, Y, Chen, L, Yang, Q. | | 登録日 | 2013-11-16 | | 公開日 | 2014-11-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A crystal structure-guided rational design switching non-carbohydrate inhibitors' specificity between two beta-GlcNAcase homologs
Sci Rep, 4, 2014
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5JI2
 | | HslU L199Q in HslUV complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ... | | 著者 | Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V. | | 登録日 | 2016-04-21 | | 公開日 | 2016-11-30 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.307 Å) | | 主引用文献 | A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis.
Structure, 24, 2016
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7V7M
 | | crystal structure of SARS-CoV-2 3CL protease | | 分子名称: | 3C-like proteinase | | 著者 | Yi, Y, Zhang, M, Ye, M. | | 登録日 | 2021-08-21 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Schaftoside inhibits 3CL pro and PL pro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19.
Acta Pharm Sin B, 12, 2022
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7WB0
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7WAZ
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7WAY
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7WB1
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4AF3
 | | Human Aurora B Kinase in complex with INCENP and VX-680 | | 分子名称: | AURORA KINASE B, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, INNER CENTROMERE PROTEIN | | 著者 | Elkins, J.M, Vollmar, M, Wang, J, Picaud, S, Arrowsmith, C.H, Edwards, A, Bountra, C, von Delft, F, Knapp, S. | | 登録日 | 2012-01-16 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal Structure of Human Aurora B in Complex with Incenp and Vx-680.
J.Med.Chem., 55, 2012
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7FEW
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7FF0
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