3WMB
Crystal structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with naphthalimide derivative Q1
Summary for 3WMB
Entry DOI | 10.2210/pdb3wmb/pdb |
Related | 3NSM 3NSN 3OZO 3OZP 3S6T 3VTR 3WMC |
Descriptor | Beta-hexosaminidase, 2-(2-{[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]amino}ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | chitinase, glycosyl hydrolase, insect, ostrinia furnacalis, hydrolase |
Biological source | Ostrinia furnacalis (Asian corn borer) |
Total number of polymer chains | 1 |
Total formula weight | 66346.73 |
Authors | |
Primary citation | Liu, T.,Guo, P.,Zhou, Y.,Wang, J.,Chen, L.,Yang, H.,Qian, X.,Yang, Q. A crystal structure-guided rational design switching non-carbohydrate inhibitors' specificity between two beta-GlcNAcase homologs Sci Rep, 4:6188-6188, 2014 Cited by PubMed: 25155420DOI: 10.1038/srep06188 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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