3WMB
Crystal structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with naphthalimide derivative Q1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Beta-hexosaminidase | polymer | 572 | 65551.9 | 1 | UniProt (Q06GJ0) Pfam (PF14845) Pfam (PF00728) In PDB | Ostrinia furnacalis (Asian corn borer) | |
| 2 | A | 2-(2-{[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]amino}ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione | non-polymer | 352.4 | 1 | Chemie (NF1) | |||
| 3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A: 23 - 594 (UniProt: Q06GJ0)
| PDB | External Database | Details |
|---|---|---|
| Leu 243 | Phe 243 | engineered mutation |
| Phe 570 | Leu 570 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 65551.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 794.8 | |
| All* | Total formula weight | 66346.7 |
