7YFH
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![BU of 7yfh by Molmil](/molmil-images/mine/7yfh) | Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine, glutamate and (R)-PYD-106 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | 著者 | Zhang, M, Zhang, J, Guo, F, Li, Y, Zhu, S. | 登録日 | 2022-07-08 | 公開日 | 2023-03-29 | 最終更新日 | 2023-05-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits. Nat.Struct.Mol.Biol., 30, 2023
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2QOH
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![BU of 2qoh by Molmil](/molmil-images/mine/2qoh) | Crystal Structure of Abl kinase bound with PPY-A | 分子名称: | 5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE, Proto-oncogene tyrosine-protein kinase ABL1 | 著者 | Zhou, T, Dalgarno, D, Zhu, X. | 登録日 | 2007-07-20 | 公開日 | 2007-09-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure of the T315I Mutant of Abl Kinase Chem.Biol.Drug Des., 70, 2007
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6KGD
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![BU of 6kgd by Molmil](/molmil-images/mine/6kgd) | Crystal structure of CaDoc0917(R49D)-CaCohA2 complex at pH 8.0 | 分子名称: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | 著者 | Feng, Y, Yao, X. | 登録日 | 2019-07-11 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules. Sci Adv, 6, 2020
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6KGE
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![BU of 6kge by Molmil](/molmil-images/mine/6kge) | Crystal structure of CaDoc0917(R16D)-CaCohA2 complex at pH 5.5 | 分子名称: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | 著者 | Feng, Y, Yao, X. | 登録日 | 2019-07-11 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules. Sci Adv, 6, 2020
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6KG8
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4MBL
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![BU of 4mbl by Molmil](/molmil-images/mine/4mbl) | Discovery of Pyrazolo[1,5a]pyrimidine-based Pim1 Inhibitors | 分子名称: | (1R,2R)-N-[3-(naphthalen-2-yl)pyrazolo[1,5-a]pyrimidin-5-yl]cyclohexane-1,2-diamine, Serine/threonine-protein kinase pim-1 | 著者 | Azevedo, R, Fischmann, T.O. | 登録日 | 2013-08-19 | 公開日 | 2013-09-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of pyrazolo[1,5-a]pyrimidine-based Pim inhibitors: A template-based approach. Bioorg.Med.Chem.Lett., 23, 2013
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3NCO
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![BU of 3nco by Molmil](/molmil-images/mine/3nco) | Crystal structure of FnCel5A from F. nodosum Rt17-B1 | 分子名称: | Endoglucanase FnCel5A, PHOSPHATE ION, peptide (ALA)(ASN)(GLU), ... | 著者 | Zheng, B.S, Yang, W, Wang, Y, Lou, Z.Y, Rao, Z.H, Feng, Y. | 登録日 | 2010-06-05 | 公開日 | 2011-06-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of FnCel5A from F. nodosum Rt17-B1 To be Published
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5TWY
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4LX4
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![BU of 4lx4 by Molmil](/molmil-images/mine/4lx4) | Crystal Structure Determination of Pseudomonas stutzeri endoglucanase Cel5A using a Twinned Data Set | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endoglucanase(Endo-1,4-beta-glucanase)protein | 著者 | Dutoit, R, Delsaute, M, Berlemont, R, Van Elder, D, Galleni, M, Bauvois, C. | 登録日 | 2013-07-29 | 公開日 | 2014-07-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.556 Å) | 主引用文献 | Crystal structure determination of Pseudomonas stutzeri A1501 endoglucanase Cel5A: the search for a molecular basis for glycosynthesis in GH5_5 enzymes. Acta Crystallogr D Struct Biol, 75, 2019
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4MJR
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![BU of 4mjr by Molmil](/molmil-images/mine/4mjr) | E. coli sliding clamp in complex with (S)-Carprofen | 分子名称: | (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2013-09-04 | 公開日 | 2013-09-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs. Chem.Biol., 21, 2014
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4MJP
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![BU of 4mjp by Molmil](/molmil-images/mine/4mjp) | E. coli sliding clamp in complex with (R)-Vedaprofen | 分子名称: | (2R)-2-(4-cyclohexylnaphthalen-1-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2013-09-04 | 公開日 | 2013-09-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.855 Å) | 主引用文献 | DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs. Chem.Biol., 21, 2014
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4MJQ
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7WKX
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![BU of 7wkx by Molmil](/molmil-images/mine/7wkx) | IL-17A in complex with the humanized antibody HB0017 | 分子名称: | ACETIC ACID, Heavy chain of HB0017 Fab, Interleukin-17A, ... | 著者 | Xu, J, Zhu, X, He, Y. | 登録日 | 2022-01-12 | 公開日 | 2022-03-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structural and functional insights into a novel pre-clinical-stage antibody targeting IL-17A for treatment of autoimmune diseases. Int.J.Biol.Macromol., 202, 2022
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8J17
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![BU of 8j17 by Molmil](/molmil-images/mine/8j17) | Crystal structure of IsPETase variant | 分子名称: | Poly(ethylene terephthalate) hydrolase | 著者 | Yin, Q.D, Wang, Y.X. | 登録日 | 2023-04-12 | 公開日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Efficient polyethylene terephthalate biodegradation by an engineered Ideonella sakaiensis PETase with a fixed substrate-binding W156 residue Green Chem, 2013
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7EA7
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![BU of 7ea7 by Molmil](/molmil-images/mine/7ea7) | crystal structure of NAP1 LIR in complex with GABARAP | 分子名称: | Gamma-aminobutyric acid receptor-associated protein, NAP1_LIR motif | 著者 | Fu, T, Pan, L. | 登録日 | 2021-03-06 | 公開日 | 2021-12-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52. Sci Adv, 7, 2021
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7EA2
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![BU of 7ea2 by Molmil](/molmil-images/mine/7ea2) | crystal structure of NAP1 FIR in complex with RB1CC1 Claw domain | 分子名称: | 5-azacytidine-induced protein 2,RB1-inducible coiled-coil protein 1, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Fu, T, Pan, L. | 登録日 | 2021-03-06 | 公開日 | 2021-12-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52. Sci Adv, 7, 2021
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7EAA
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4N96
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4N95
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![BU of 4n95 by Molmil](/molmil-images/mine/4n95) | E. coli sliding clamp in complex with 5-chloroindoline-2,3-dione | 分子名称: | 5-chloro-1H-indole-2,3-dione, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2013-10-19 | 公開日 | 2013-11-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
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4N73
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4N98
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5TWU
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![BU of 5twu by Molmil](/molmil-images/mine/5twu) | Structure of Maternal Embryonic Leucine Zipper Kinase | 分子名称: | Maternal embryonic leucine zipper kinase | 著者 | Li, Q, Seo, H.-S, Huang, H.-T, Gray, N.S, Dhe-Paganon, S, Eck, M.J. | 登録日 | 2016-11-14 | 公開日 | 2017-11-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.603 Å) | 主引用文献 | MELK is not necessary for the proliferation of basal-like breast cancer cells. Elife, 6, 2017
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7XKC
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![BU of 7xkc by Molmil](/molmil-images/mine/7xkc) | Crystal structure of Daucus Carrot hypoglycemic peptide (DCHP) | 分子名称: | DCHP, SULFATE ION | 著者 | Guo, T, Ren, J.Q, Wang, L, Shi, Y.W, Feng, W. | 登録日 | 2022-04-19 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Characterization of a thermostable, protease-tolerant inhibitor of alpha-glycosidase from carrot: A potential oral additive for treatment of diabetes. Int.J.Biol.Macromol., 209, 2022
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5V6N
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4N9A
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![BU of 4n9a by Molmil](/molmil-images/mine/4n9a) | E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid | 分子名称: | (1R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yin, Z, Oakley, A.J. | 登録日 | 2013-10-19 | 公開日 | 2013-11-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
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