4MJP

E. coli sliding clamp in complex with (R)-Vedaprofen

Summary for 4MJP

Entry DOI	10.2210/pdb4mjp/pdb
Related	4MJQ 4MJR
Descriptor	DNA polymerase III subunit beta, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, ... (7 entities in total)
Functional Keywords	poliii beta, sliding clamp, dnan, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Escherichia coli
Cellular location	Cytoplasm: P0A988
Total number of polymer chains	2
Total formula weight	82202.42
Authors	Yin, Z.,Oakley, A.J. (deposition date: 2013-09-04, release date: 2013-09-18, Last modification date: 2023-09-20)
Primary citation	Yin, Z.,Wang, Y.,Whittell, L.R.,Jergic, S.,Liu, M.,Harry, E.,Dixon, N.E.,Kelso, M.J.,Beck, J.L.,Oakley, A.J. DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs. Chem.Biol., 21:481-487, 2014 Cited by PubMed: 24631121 DOI: 10.1016/j.chembiol.2014.02.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.855 Å)

Structure validation